Academic Journal

Insights into the pattern of choroidal vascularity index changes in idiopathic macular hole

التفاصيل البيبلوغرافية
العنوان: Insights into the pattern of choroidal vascularity index changes in idiopathic macular hole
المؤلفون: Xia, Huaqin, Yang, Jiarui, Hou, Qingyi, Wu, Xinchun, Wang, Changguan, Li, Xuemin
المساهمون: Peking University Medicine Sailing Program for Young Scholars’ Scientific & Technological Innovation
المصدر: Scientific Reports ; volume 14, issue 1 ; ISSN 2045-2322
بيانات النشر: Springer Science and Business Media LLC
سنة النشر: 2024
الوصف: This retrospective study aimed to investigate the changes in choroidal vascularity index (CVI) before and after surgery for idiopathic macular hole (MH). Enhanced depth imaging optical coherence tomography (EDI-OCT) images were analyzed at baseline and at 1-week, 1-month, and 3-month postoperative visits. A total of 97 patients (97 eyes) were included in the study. At baseline, overall CVI and macular CVI showed negative correlation with axial length (AL) and positive correlation with central corneal thickness (CCT). There were no significant differences in macular CVI or overall CVI between affected and healthy eyes, as well as in subgroup analysis of different stages of macular CVI. Following surgery, there was a significant decrease in CVI at 1 week postoperatively, followed by a gradual recovery to baseline levels over time. The observed changes in CVI may be attributed to factors such as air tamponade, pressure changes, and photoreceptor metabolism. This study provides insights into the pattern of CVI changes associated with MH surgery. The findings suggest that stage 4 MH is associated with decreased macular CVI in affected eyes. These results contribute to a better understanding of the effects of surgery on choroidal blood flow in MH patients.
نوع الوثيقة: article in journal/newspaper
اللغة: English
DOI: 10.1038/s41598-024-51739-8
الاتاحة: http://dx.doi.org/10.1038/s41598-024-51739-8
https://www.nature.com/articles/s41598-024-51739-8.pdf
https://www.nature.com/articles/s41598-024-51739-8
Rights: https://creativecommons.org/licenses/by/4.0 ; https://creativecommons.org/licenses/by/4.0
رقم الانضمام: edsbas.1A098972
قاعدة البيانات: BASE
الوصف
DOI:10.1038/s41598-024-51739-8