التفاصيل البيبلوغرافية
| العنوان: |
POSTER VIEWING SESSION - ENDOMETRIOSIS, ENDOMETRIUM, IMPLANTATION AND FALLOPIAN TUBE |
| المؤلفون: |
Palial, K.K., Drury, J., Heathcote, L., Valentijin, A., Farquharson, R.G., Gazvani, R., Rudland, P.S., Hapangama, D.K., Celik, N., Celik, O., Aktan, E., Ozerol, E., Celik, E., Bozkurt, K., Paran, H., Hascalik, S., Ozerol, I., Arase, T., Maruyama, T., Uchida, H., Miyazaki, K., Oda, H., Uchida-Nishikawa, S., Kagami, M., Yamazaki, A., Tamaki, K., Yoshimura, Y., De Vos, M., Ortega, C., Smitz, J., Van Vaerenbergh, I., Bourgain, C., Devroey, P., Luciano, D., Exacoustos, C., Zupi, E., Luciano, A.A., Arduini, D., Palomino, W.A., Argandona, F., Kohen, P., Azua, R., Scarella, A., Devoto, L., McKinnon, B., Bersinger, N.A., Mueller, M.D., Bonavita, M., Mattila, M., Ferreira, F.P., Maia-Filho, V., Rocha, A.M., Serafini, P., Motta, E.L.A., Kim, H., Kim, C.H., You, R.M., Nah, H.Y., Lee, J.W., Kang, H.J., Kang, B.M., Letur - Köenirsch, H., Haouzi, D., Olivennes, F., Rouleau, C., Cohen-Bacri, P., Déchaud, H., Hamamah, S., DHooghe, T., Hummelshoj, L., Dunselman, G.A.J., Dirksen, C.D., EndoCost Consortium, W.E.R.F., Simoens, S., Novembri, R., Luisi, S., Carrarelli, P., Rocha, A.L.L., Toti, P., Reis, F.M., Florio, P., Petraglia, F., Bruce, K.D., Sadek, K.H., Macklon, N., Cagampang, F.R., Cheong, Y., Goudakou, M., Kalogeraki, A., Matalliotakis, I., Papatheodorou, A., Pasadaki, T., Karkanaki, A., Prapas, I., Panagiotidis, I., Kasapi, E., Barlow, D., Oliver, J., Loumaye, E., Khanmohammadi, M., kazemnejad, S., darzi, S., Khanjani, S., Zarnani, A., Akhondi, M., Tan, C.W., Ng, C.P., Loh, S.F., Tan, H.H., Choolani, M., Griffith, L., Chan, J., Andersson, K.L., Sundqvist, J., Scarselli, G., Gemzell-Danielsson, K., Lalitkumar, P.G., Jana, S., Chattopadhyay, R., Datta Ray, C., Chaudhury, K., Chakravarty, B.N., Hannan, N., Evans, J., Hincks, C., Rombauts, L.J.F., Salamonsen, L.A., Choi, D., Lee, J., Park, J., Chang, H., Kim, M., Hwang, K., Takeuchi, K., Kurematsu, T., Fukumoto, Y., Yuki, Y., Kuroki, Y., Homan, Y., Sata, Y., Takeuchi, M., Muñoz Muñoz, E., Ortiz Olivera, G., Fernandez Lopez, I., Martinez Martinez, B., Aguilar Prieto, J., Portela Perez, S., Pellicer Martinez, A., Keltz, M., Sauerbrun, M., Breborowicz, A., Gonzales, E., Vicente-Muñoz, S., Puchades-Carrasco, L., Morcillo, I., Hidalgo, J.J., Gilabert-Estelles, J., Novella-Maestre, E., Pellicer, A., Pineda-Lucena, A., Yavorovskaya, K.A., Okhtyrskaya, T.A., Demura, T.A., Faizulina, N.M., Ezhova, L.S., Kogan, E.A., Bilibio, J.P., Souza, C.A.B., Rodini, G.P., Genro, V., Andreoli, C.G., de Conto, E., Cunha-Filho, J.S.L., Saare, M., Sõritsa, D., Järva, L., Vaidla, K., Palta, P., Laan, M., Karro, H., Sõritsa, A., Salumets, A., Peters, M., Miskova, A., Pilmane, M., Rezeberga, D., Assou, S., Létur, H., Piomboni, P., Stendardi, A., Gambera, L., De Leo, V., Focarelli, R., Tamm, K., Simm, J., Metsis, M., Vodolazkaia, A., Fassbender, A., Kyama, C.M., Bokor, A., Schols, D., Huskens, D., Meuleman, C., Peeraer, K., Tomassetti, C., DHooghe, T.M., Machens, K., Afhüppe, W., Schulz, A., Diefenbach, K., Schütt, B., Faustmann, T., Reischl, J., Altmäe, S., Reimand, J., Laisk, T., Hovatta, O., Kolde, R., Vilo, J., Stavreus-Evers, A., Lee, J.H., Kim, S.G., Kim, Y.Y., Park, I.H., Sun, H.G., Lee, K.H., Ezoe, K., Kawano, H., Yabuuchi, A., Ochiai, K., Nagashima, H., Osada, H., Kagawa, N., Kato, O., Tamura, I., Asada, H., Taketani, T., Tamura, H., Sugino, N., Garcia Velasco, J., Prieto, L., Quesada, J.F., Cambero, O., Toribio, M., Hur, C.Y., Lim, K.S., Lee, W.D., Lim, J.H., Germeyer, A., Nelson, L., Graham, A., Jauckus, J., Strowitzki, T., Lessey, B., Gyulmamedova, I., Illina, O., Illin, I., Mogilevkina, I., Chaika, A., Nosenko, O., Boykova, I., Gulmamedova, E., Isik, H., Moraloglu, O., Seven, A.L.I., Kilic, S., Erkayiran, U., Caydere, M., Batioglu, S., Alhalabi, M., Samawi, S., Taha, A., Kafri, N., Modi, S., Khatib, A., Sharif, J., Othman, A., Lancuba, S., Branzini, C., Lopez, M., Baricalla, A., Cristina, C., Chen, J., Jiang, Y., Zhen, X., Hu, Y., Yan, G., Sun, H., Mizumoto, J., Ueno, J., Carvalho, F.M., Casals, G., Ordi, J., Guimerà, M., Creus, M., Fábregues, F., Casamitjana, R., Carmona, F., Balasch, J., Choi, Y.S., Kim, K.C., Kim, K.H., Lee, B.S., Kim, S.H., Overbergh, L., Verdrengh, E., Kyama, C., Waelkens, E., Mathieu, C., Iwasa, T., Hatano, K., Hasegawa, E., Ito, H., Isaka, K., L. Rocha, A.L., Reis, F., Lee, K.S., Joo, J.K., Son, J.B., Choi, J.R., Vidali, A., Barad, D.H., Gleicher, N., Sayyah-Melli, M., Kazemi-Shishvan, M. |
| بيانات النشر: |
Oxford University Press |
| سنة النشر: |
2011 |
| المجموعة: |
HighWire Press (Stanford University) |
| مصطلحات موضوعية: |
Poster Presentations |
| الوصف: |
Introduction: Degradation of basement membrane (BM) is reported to be involved in the metastatic process of cancers. BM components, collagen four (COLIV) and laminin, have also been shown to be aberrantly expressed in the benign metastatic disease of endometriosis. Cytokeratin 5/6 (Ck5/6) and podocalyxin-like protein (PODXL) have been proposed as markers of stem cells. We aim to investigate if an alteration of BM integrity is associated with differential expression of PODXL and Ck5/6, in endometrium collected from endometriosis patients. Material and Methods: Eutopic endometrium was collected from 16 patients with endometriosis; n = 8 in the window of implantation (WOI, day 21 ± 2), and n = 8 in the late secretory phase (LSP, day 26 ± 2) when remodelling of BM components is known to peak. The inclusion criteria for this group were: (1) reproductive women with regular menstrual cycles; (2) surgically diagnosed active peritoneal endometriosis; and (3) history of dysmenorrhoea and/or chronic pelvic pain. Exclusion criteria included hormonal treatment in the previous three months. Samples were also obtained from 18 normal fertile controls; n = 10 during the WOI and n = 8 during the LSP. These women had surgically excluded endometriosis and at least one successful pregnancy. In each specimen the expression of COLIV, laminin, PODXL and CK5/6 were studied using immunohistochemistry. The thickness and staining intensity of immuno-located BM components supporting glandular and luminal epithelium was separately measured with a computer-assisted image analysis system and a semi-quantitative scoring system. A previously reported semi-quantitative, modified “quickscore” method which consolidates both staining intensity and the percentage coverage in glandular secretions (Schiessl et al. Placenta 2009) was used to analyse PODXL immuno-staining in at least 10 glands per section. Additionally, a semi-quantitative scoring system was used to evaluate PODXL staining intensity in vascular endothelium and Ck5/6 staining intensity in ... |
| نوع الوثيقة: |
text |
| وصف الملف: |
text/html |
| اللغة: |
English |
| Relation: |
http://humrep.oxfordjournals.org/cgi/content/short/26/suppl_1/i202; http://dx.doi.org/10.1093/humrep/26.s1.80 |
| DOI: |
10.1093/humrep/26.s1.80 |
| الاتاحة: |
http://humrep.oxfordjournals.org/cgi/content/short/26/suppl_1/i202
https://doi.org/10.1093/humrep/26.s1.80 |
| Rights: |
Copyright (C) 2011, European Society of Human Reproduction and Embryology |
| رقم الانضمام: |
edsbas.1992B596 |
| قاعدة البيانات: |
BASE |