التفاصيل البيبلوغرافية
| العنوان: |
Human platelet 6-phosphofructokinase . Relation between inhibition by Mg · ATP2 - and cooperativity towards fructose 6-phosphate and investigations on the formation of a ternary complex |
| المؤلفون: |
Akkerman, Jan Willem N., Gorter, Gertie, Over, Jan, Sixma, J.J., Staal, Gerard E.J. |
| سنة النشر: |
1975 |
| مصطلحات موضوعية: |
Biologie |
| الوصف: |
Human platelet 6-phosphofructokinase (EC 2.7.1.11) shows cooperativity towards Fru-6-P and is allosterically inhibited by high Mg . ATP2− concentrations. No relation could be demonstrated between the cooperativity towards Fru-6-P and the inhibition by Mg . ATP2−. Increasing the concentrations of Mg . ATP2− only raised the apparent Km values for Fru-6-P, but did not change the Hill constants. a possible formation of a Mg . ATP2− : enzyme . Fru-6-P complex during catalysis was investigated. Our calculations suggest that such a ternary complex is indeed formed during the reaction. |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
image/pdf |
| اللغة: |
English |
| تدمد: |
0005-2744 |
| Relation: |
https://dspace.library.uu.nl/handle/1874/16089 |
| الاتاحة: |
https://dspace.library.uu.nl/handle/1874/16089 |
| Rights: |
info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: |
edsbas.193B32F5 |
| قاعدة البيانات: |
BASE |