التفاصيل البيبلوغرافية
| العنوان: |
Relationship between donor genotype, stage of infection and transfusion transmission rate. |
| المؤلفون: |
M. Khalid F. Salamat (10163942), A. Richard Alejo Blanco (10163945), Sandra McCutcheon (209180), Kyle B. C. Tan (10163948), Paula Stewart (113704), Helen Brown (423601), Allister Smith (10163951), Christopher de Wolf (209200), Martin H. Groschup (69888), Dietmar Becher (10163954), Olivier Andréoletti (75339), Marc Turner (209250), Jean C. Manson (9354320), E. Fiona Houston (10163957) |
| سنة النشر: |
2021 |
| المجموعة: |
Smithsonian Institution: Digital Repository |
| مصطلحات موضوعية: |
Medicine, Microbiology, Cell Biology, Molecular Biology, Pharmacology, Biotechnology, Immunology, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Donor PRNP genotype, blood transfusion, component, PMCA, on-going risk reduction measures, blood cells, BSE, infection Variant Creutzfeldt-Jakob., protein misfolding cyclic amplification, 4 months post infection, prion disease, WBC, transfusion transmission rates |
| الوصف: |
Each point on the chart represents an individual infected donor sheep, showing the number of corresponding transfusion recipients infected (all components) plotted against the stage of survival period at which blood was collected (%SP = time from infection to blood collection x 100/time from infection to culling). The donor PRNP codon 141 genotypes are represented by different symbols: 141LL–open diamonds; 141FF–closed triangles; 141LF–open circles. The longer survival periods of 141FF and 141LF compared to 141LL sheep mean that they were at an earlier stage of infection when they donated blood for transfusion (10 months post infection for all donors). |
| نوع الوثيقة: |
still image |
| اللغة: |
unknown |
| Relation: |
https://figshare.com/articles/figure/Relationship_between_donor_genotype_stage_of_infection_and_transfusion_transmission_rate_/14055485 |
| DOI: |
10.1371/journal.ppat.1009276.g002 |
| الاتاحة: |
https://doi.org/10.1371/journal.ppat.1009276.g002 |
| Rights: |
CC BY 4.0 |
| رقم الانضمام: |
edsbas.18DB0F4C |
| قاعدة البيانات: |
BASE |