Academic Journal
Calcium carbonate-enriched pumpkin affects calcium status in ovariectomized rats
| العنوان: | Calcium carbonate-enriched pumpkin affects calcium status in ovariectomized rats |
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| المؤلفون: | Wawrzyniak, Natalia, Gramza-Michałowska, Anna, Kurzawa, Paweł, Kołodziejski, Paweł, Suliburska, Joanna |
| المساهمون: | Narodowe Centrum Nauki |
| المصدر: | Journal of Food Science and Technology ; volume 60, issue 4, page 1402-1413 ; ISSN 0022-1155 0975-8402 |
| بيانات النشر: | Springer Science and Business Media LLC |
| سنة النشر: | 2023 |
| الوصف: | Calcium carbonate (CaCO 3 )-enriched pumpkin may serve as a good source of calcium for patients diagnosed with osteoporosis. In this study, we aimed to determine the effect of CaCO 3 -enriched pumpkin on Ca status in ovariectomized rats. The study included 40 female Wistar rats divided into five groups (n = 8). One group was fed with a standard diet (control group), while the other four groups were ovariectomized and received a standard diet (control ovariectomized group), or a diet containing CaCO 3 -enriched pumpkin, alendronate, or both. The nutritional intervention lasted 12 weeks, and then the rats were euthanized. Tissue and blood samples were collected and assessed for the levels of total Ca, estradiol, parathyroid hormone, and procollagen type I N propeptide. In addition, a histological analysis was performed on femurs. The results of the study suggest that CaCO 3 -enriched pumpkin can increase Ca content in femurs and improve bone recovery in ovariectomized rats. Furthermore, enriched pumpkin contributes to Ca accumulation in the kidneys, and this effect is more pronounced in combination with alendronate. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1007/s13197-023-05686-3 |
| DOI: | 10.1007/s13197-023-05686-3.pdf |
| DOI: | 10.1007/s13197-023-05686-3/fulltext.html |
| الاتاحة: | http://dx.doi.org/10.1007/s13197-023-05686-3 https://link.springer.com/content/pdf/10.1007/s13197-023-05686-3.pdf https://link.springer.com/article/10.1007/s13197-023-05686-3/fulltext.html |
| Rights: | https://creativecommons.org/licenses/by/4.0 ; https://creativecommons.org/licenses/by/4.0 |
| رقم الانضمام: | edsbas.18AD3275 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/s13197-023-05686-3 |
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