Academic Journal
Current knowledge and future challenges in takotsubo syndrome: Part 2-treatment and prognosis
العنوان: | Current knowledge and future challenges in takotsubo syndrome: Part 2-treatment and prognosis |
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المؤلفون: | Santoro F., Mallardi A., Leopizzi A., Vitale E., Rawish E., Stiermaier T., Eitel I., Brunetti N. D. |
المساهمون: | Santoro, F., Mallardi, A., Leopizzi, A., Vitale, E., Rawish, E., Stiermaier, T., Eitel, I., Brunetti, N. D. |
سنة النشر: | 2021 |
المجموعة: | Università degli Studi di Foggia: CINECA IRIS Institutional Research Information System |
مصطلحات موضوعية: | Apical ballooning, Outcome, Prognosi, Takotsubo syndrome, Therapy |
الوصف: | Takotsubo syndrome (TTS) represents a form of acute heart failure featured by reversible left ventricular systolic dysfunction. The management during the acute phase is mainly performed with supportive pharmacological (diuretics, ACE-inhibitors/angiotensin-receptor blockers (ARBs), anticoagulants, antiarrhythmics, non-catecholamine inotropics (levosimendan), and non-pharmacological (mechanical circulatory and respiratory support) therapy, due to the wide clinical presentation and course of the disease. However, there is a gap in evidence and there are no randomized and adequately powered studies on clinical effectiveness of therapeutic approaches. Some evidence supports the use ACE-inhibitors/ARBs at long-term. A tailored approach based on cardiovascular and noncardiovascular risk factors is strongly suggested for long-term management. The urgent need for evidence-based treatment approaches is also reflected by the prognosis following TTS. The acute phase of the disease can be accompanied by various cardiovascular complications. In addition, long term outcome of TTS patients is also related to non-cardiovascular comorbidities. Physical triggers such as hypoxia and acute neurological disorders in TTS are associated with a poor outcome. |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
Relation: | info:eu-repo/semantics/altIdentifier/pmid/33530545; info:eu-repo/semantics/altIdentifier/wos/WOS:000615334300001; volume:10; issue:3; firstpage:1; lastpage:9; numberofpages:9; journal:JOURNAL OF CLINICAL MEDICINE; https://hdl.handle.net/11369/416558; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85103631353 |
DOI: | 10.3390/jcm10030468 |
الاتاحة: | https://hdl.handle.net/11369/416558 https://doi.org/10.3390/jcm10030468 |
رقم الانضمام: | edsbas.1814D0B7 |
قاعدة البيانات: | BASE |
DOI: | 10.3390/jcm10030468 |
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