Academic Journal

Current knowledge and future challenges in takotsubo syndrome: Part 2-treatment and prognosis

التفاصيل البيبلوغرافية
العنوان: Current knowledge and future challenges in takotsubo syndrome: Part 2-treatment and prognosis
المؤلفون: Santoro F., Mallardi A., Leopizzi A., Vitale E., Rawish E., Stiermaier T., Eitel I., Brunetti N. D.
المساهمون: Santoro, F., Mallardi, A., Leopizzi, A., Vitale, E., Rawish, E., Stiermaier, T., Eitel, I., Brunetti, N. D.
سنة النشر: 2021
المجموعة: Università degli Studi di Foggia: CINECA IRIS Institutional Research Information System
مصطلحات موضوعية: Apical ballooning, Outcome, Prognosi, Takotsubo syndrome, Therapy
الوصف: Takotsubo syndrome (TTS) represents a form of acute heart failure featured by reversible left ventricular systolic dysfunction. The management during the acute phase is mainly performed with supportive pharmacological (diuretics, ACE-inhibitors/angiotensin-receptor blockers (ARBs), anticoagulants, antiarrhythmics, non-catecholamine inotropics (levosimendan), and non-pharmacological (mechanical circulatory and respiratory support) therapy, due to the wide clinical presentation and course of the disease. However, there is a gap in evidence and there are no randomized and adequately powered studies on clinical effectiveness of therapeutic approaches. Some evidence supports the use ACE-inhibitors/ARBs at long-term. A tailored approach based on cardiovascular and noncardiovascular risk factors is strongly suggested for long-term management. The urgent need for evidence-based treatment approaches is also reflected by the prognosis following TTS. The acute phase of the disease can be accompanied by various cardiovascular complications. In addition, long term outcome of TTS patients is also related to non-cardiovascular comorbidities. Physical triggers such as hypoxia and acute neurological disorders in TTS are associated with a poor outcome.
نوع الوثيقة: article in journal/newspaper
اللغة: English
Relation: info:eu-repo/semantics/altIdentifier/pmid/33530545; info:eu-repo/semantics/altIdentifier/wos/WOS:000615334300001; volume:10; issue:3; firstpage:1; lastpage:9; numberofpages:9; journal:JOURNAL OF CLINICAL MEDICINE; https://hdl.handle.net/11369/416558; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85103631353
DOI: 10.3390/jcm10030468
الاتاحة: https://hdl.handle.net/11369/416558
https://doi.org/10.3390/jcm10030468
رقم الانضمام: edsbas.1814D0B7
قاعدة البيانات: BASE