Academic Journal
Reliability, Validity, and Responsiveness of InFLUenza Patient-Reported Outcome (FLU-PRO (c)) Scores in Influenza-Positive Patients
| العنوان: | Reliability, Validity, and Responsiveness of InFLUenza Patient-Reported Outcome (FLU-PRO (c)) Scores in Influenza-Positive Patients |
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| المؤلفون: | Powers, JH, Bacci, ED, Lourdes Guerrero, M, Leidy, NK, Stringer, S, Kim, K, Memoli, MJ, Han, A, Fairchok, MP, Chen, W-J, Arnold, JC, Danaher, PJ, Lalani, T, Ridore, M, Burgess, TH, Millar, EV, Hernandez, A, Rodriguez-Zulueta, P, Smolskis, MC, Ortega-Gallegos, H, Pett, S, Fischer, W, Gillor, D, Moreno Macias, L, DuVal, A, Rothman, R, Dugas, A, Ruiz-Palacios, GM |
| المصدر: | Value in Health , 21 (2) pp. 210-218. (2018) |
| بيانات النشر: | ELSEVIER SCIENCE INC |
| سنة النشر: | 2018 |
| المجموعة: | University College London: UCL Discovery |
| مصطلحات موضوعية: | influenza, patient-reported outcome, psychometric, reliability, responsiveness, validity |
| الوصف: | OBJECTIVES: To assess the reliability, validity, and responsiveness of InFLUenza Patient-Reported Outcome (FLU-PRO©) scores for quantifying the presence and severity of influenza symptoms. METHODS: An observational prospective cohort study of adults (≥18 years) with influenza-like illness in the United States, the United Kingdom, Mexico, and South America was conducted. Participants completed the 37-item draft FLU-PRO daily for up to 14 days. Item-level and factor analyses were used to remove items and determine factor structure. Reliability of the final tool was estimated using Cronbach α and intraclass correlation coefficients (2-day reliability). Convergent and known-groups validity and responsiveness were assessed using global assessments of influenza severity and return to usual health. RESULTS: Of the 536 patients enrolled, 221 influenza-positive subjects comprised the analytical sample. The mean age of the patients was 40.7 years, 60.2% were women, and 59.7% were white. The final 32-item measure has six factors/domains (nose, throat, eyes, chest/respiratory, gastrointestinal, and body/systemic), with a higher order factor representing symptom severity overall (comparative fit index = 0.92; root mean square error of approximation = 0.06). Cronbach α was high (total = 0.92; domain range = 0.71–0.87); test-retest reliability (intraclass correlation coefficient, day 1–day 2) was 0.83 for total scores and 0.57 to 0.79 for domains. Day 1 FLU-PRO domain and total scores were moderately to highly correlated (≥0.30) with Patient Global Rating of Flu Severity (except nose and throat). Consistent with known-groups validity, scores differentiated severity groups on the basis of global rating (total: F = 57.2, P < 0.001; domains: F = 8.9–67.5, P < 0.001). Subjects reporting return to usual health showed significantly greater (P < 0.05) FLU-PRO score improvement by day 7 than did those who did not, suggesting score responsiveness. CONCLUSIONS: Results suggest that FLU-PRO scores are reliable, valid, and ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | text |
| اللغة: | English |
| Relation: | https://discovery.ucl.ac.uk/id/eprint/10056376/1/Chester_PDFsam_merge.pdf; https://discovery.ucl.ac.uk/id/eprint/10056376/ |
| الاتاحة: | https://discovery.ucl.ac.uk/id/eprint/10056376/1/Chester_PDFsam_merge.pdf https://discovery.ucl.ac.uk/id/eprint/10056376/ |
| Rights: | open |
| رقم الانضمام: | edsbas.1732EAAC |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |