Academic Journal
Efficacy of sunitinib in patients with imatinib-resistant gastrointestinal stromal tumors
| العنوان: | Efficacy of sunitinib in patients with imatinib-resistant gastrointestinal stromal tumors |
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| المؤلفون: | Çubukcu, Sinem, Kanat, Özkan, Çubukcu, Erdem, Ölmez, Ömer Fatih, Canhoroz, Mustafa, Avcı, Nilüfer, Hartavi, Mustafa, Deligönül, Adem, Seyhan, Serdar, Ayyıldız, Aylin, Taşdemir, Ünal, Manavoğlu, Osman |
| المساهمون: | Tıp Fakultesi, Tıp Fakültesi, Tıbbi Onkoloji Bilim Dalı, İç Hastalıkları Ana Bilim Dalı, ÇUBUKÇU, SİNEM, Kanat, Özkan, ÇUBUKÇU, ERDEM, Ölmez, Ömer Fatih, Canhoroz, Mustafa, Avcı, Nilüfer, Hartavi, Mustafa, DELİGÖNÜL, ADEM, Seyhan, Serdar, Ayyıldız, Aylin, Taşdemir, Ünal, Manavoğlu, Osman, JJB-0254-2023, JRU-4028-2023, JGT-4101-2023, DJG-4827-2022, CJW-6018-2022, CCT-7946-2022, CUI-5353-2022, JHC-1731-2023, DSI-5869-2022, KGG-2754-2024, KBV-2934-2024, FLP-9613-2022 |
| بيانات النشر: | Derman Medical Publ |
| سنة النشر: | 2014 |
| المجموعة: | Açık Erişim@BUU (Bursa Uludağ Üniversitesi) |
| مصطلحات موضوعية: | Cancer, Sunitinib, Gastrointestinal stromal tumors, General & internal medicine |
| الوصف: | Aim: In this study, the efficacy of sunitinib in patients with imatinib-resistant gastrointestinal stromal tumors (GISTs) was investigated. Material and Method: A total of 11 imatinib-resistant GIST patients who have sufficient information about their medical treatment and outcome were retrospectively analyzed. Results: Partial response was observed in only two patients, and five patients achieved stable disease. Progression free survival and overall time was 8.8 months and 12 months, respectively. Sunitinib was relatively well tolerated. Almost all patients experienced one or more treatment-related adverse event. Discussion: Based on our limited experience, we concluded that sunitinib is reasonable treatment option for patients with imatinibresistant GIST. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | Makale - Uluslararası Hakemli Dergi; Journal of Clinical and Analytical Medicine; https://doi.org/10.4328/JCAM.1375; https://hdl.handle.net/11452/46054; 000215563900013 |
| DOI: | 10.4328/JCAM.1375 |
| الاتاحة: | https://hdl.handle.net/11452/46054 https://doi.org/10.4328/JCAM.1375 https://ia801609.us.archive.org/5/items/efficacy-of-sunitinib-in-patients-with-imatinib-resistant-gastrointestinal-stromal-tumors/1375.pdf |
| Rights: | info:eu-repo/semantics/closedAccess |
| رقم الانضمام: | edsbas.16C61834 |
| قاعدة البيانات: | BASE |
| DOI: | 10.4328/JCAM.1375 |
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