Academic Journal
Estimating the basic reproduction number at the beginning of an outbreak
| العنوان: | Estimating the basic reproduction number at the beginning of an outbreak |
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| المؤلفون: | Boonpatcharanon, Sawitree, Heffernan, Jane M., Jankowski, Hanna |
| المساهمون: | Mariño, Inés P., canadian network for research and innovation in machining technology, natural sciences and engineering research council of canada |
| المصدر: | PLOS ONE ; volume 17, issue 6, page e0269306 ; ISSN 1932-6203 |
| بيانات النشر: | Public Library of Science (PLoS) |
| سنة النشر: | 2022 |
| المجموعة: | PLOS Publications (via CrossRef) |
| الوصف: | We compare several popular methods of estimating the basic reproduction number, R 0 , focusing on the early stages of an epidemic, and assuming weekly reports of new infecteds. We study the situation when data is generated by one of three standard epidemiological compartmental models: SIR, SEIR, and SEAIR; and examine the sensitivity of the estimators to the model structure. As some methods are developed assuming specific epidemiological models, our work adds a study of their performance in both a well-specified (data generating model and method model are the same) and miss-specified (data generating model and method model differ) settings. We also study R 0 estimation using Canadian COVID-19 case report data. In this study we focus on examples of influenza and COVID-19, though the general approach is easily extendable to other scenarios. Our simulation study reveals that some estimation methods tend to work better than others, however, no singular best method was clearly detected. In the discussion, we provide recommendations for practitioners based on our results. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1371/journal.pone.0269306 |
| الاتاحة: | http://dx.doi.org/10.1371/journal.pone.0269306 https://dx.plos.org/10.1371/journal.pone.0269306 |
| Rights: | http://creativecommons.org/licenses/by/4.0/ |
| رقم الانضمام: | edsbas.16BD1769 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1371/journal.pone.0269306 |
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