Academic Journal
Effect of Ramadan fasting on salivary IgA, serum IgA, IL-17, and IL-22 levels
| العنوان: | Effect of Ramadan fasting on salivary IgA, serum IgA, IL-17, and IL-22 levels |
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| المؤلفون: | Soleimanifar, Narjes, Assadiasl, Sara, Alamolhoda, Mohammad Hassan, Nateghpour, Mehdi, Arani, Mahmoud Motavassel, Sadr, Maryam, Mohebbi, Bahareh, Mojtahedi, Hanieh, Nicknam, Mohammad Hossein |
| المساهمون: | Tehran University of Medical Sciences and Health Services |
| المصدر: | Nutrition and Health ; volume 29, issue 3, page 591-597 ; ISSN 0260-1060 2047-945X |
| بيانات النشر: | SAGE Publications |
| سنة النشر: | 2022 |
| الوصف: | Background: nutritional factors might affect the number and function of immune cells for instance the production of cytokines and immunoglobulins. Ramadan fasting is intermittent abstinence from eating and drinking for almost four weeks. Aim: The present study aimed to investigate the influence of intermittent fasting on serum IgA, salivary IgA (sIgA), interleukin (IL)-17, and IL-22 levels. Methods: 40 healthy men aged 19–29 years were evaluated before and during the fourth week of Ramadan fasting for IgA levels by the nephelometric method as well as salivary IgA (sIgA), IL-17, and IL-22 amounts using enzyme-linked immunosorbent assay (ELISA). Results: serum IgA levels reduced significantly at the end of Ramadan fasting (225.8 ± 87 vs. 196 ± 70 mg/dl) (p-value<0.001); however, sIgA amounts did not differ between before and the last week of Ramadan. Serum IL-17 reduced significantly (2.93 ± 1.51 vs. 2.17 ± 1.33 pg/ml) (p-value = 0.006) whereas IL-22 levels remained approximately unchanged. Summary: four weeks of intermittent fasting during Ramadan reduced the serum levels of IgA and IL-17 but did not affect the production of sIgA and IL-22. These findings indicate a limited impact of intermittent fasting on mucosal immunity. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1177/02601060221092203 |
| الاتاحة: | https://doi.org/10.1177/02601060221092203 https://journals.sagepub.com/doi/pdf/10.1177/02601060221092203 https://journals.sagepub.com/doi/full-xml/10.1177/02601060221092203 |
| Rights: | https://journals.sagepub.com/page/policies/text-and-data-mining-license |
| رقم الانضمام: | edsbas.163B964F |
| قاعدة البيانات: | BASE |
| DOI: | 10.1177/02601060221092203 |
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