التفاصيل البيبلوغرافية
| العنوان: |
Monitoring the effects of dexamethasone treatment by MRI using in vivo iron oxide nanoparticle-labeled macrophages |
| المؤلفون: |
Gramoun, Azza, Crowe, Lindsey, Maurizi, Lionel, Wirth, Wolfgang, Tobalem, Frank, Grosdemange, Kerstin, Coullerez, Geraldine, Eckstein, Felix, Koenders, Marije I, Van den Berg, Wim B, Hofmann, Heinrich, Vallée, Jean-Paul |
| المصدر: |
ISSN: 1478-6354 ; Arthritis research & therapy, vol. 16, no. 3 (2014) R131. |
| سنة النشر: |
2014 |
| المجموعة: |
Université de Genève: Archive ouverte UNIGE |
| مصطلحات موضوعية: |
info:eu-repo/classification/ddc/616.0757, Animals, Anti-Inflammatory Agents/pharmacology, Antigens, CD/metabolism, Differentiation, Myelomonocytic/metabolism, Arthritis, Experimental/drug therapy/metabolism/radiography, Contrast Media/diagnostic use, Dexamethasone/pharmacology, Dose-Response Relationship, Drug, Drug Monitoring/methods, Edema/drug therapy/metabolism/radiography, Female, Ferrocyanides/chemistry, Gadolinium DTPA/diagnostic use, Immunohistochemistry, Knee Joint/chemistry/drug effects/radiography, Macrophages/chemistry/drug effects/radiography, Magnetic Resonance Imaging/methods, Magnetite Nanoparticles/chemistry, Rats, Inbred Lew, Reproducibility of Results, Staining and Labeling/methods, Synovial Membrane/drug effects/pathology/radiography |
| الوصف: |
Rheumatoid arthritis (RA) is a chronic disease causing recurring inflammatory joint attacks. These attacks are characterized by macrophage infiltration contributing to joint destruction. Studies have shown that RA treatment efficacy is correlated to synovial macrophage number. The aim of this study was to experimentally validate the use of in vivo superparamagnetic iron oxide nanoparticle (SPION) labeled macrophages to evaluate RA treatment by MRI. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/24957862; https://archive-ouverte.unige.ch/unige:77352; unige:77352 |
| الاتاحة: |
https://archive-ouverte.unige.ch/unige:77352 |
| Rights: |
info:eu-repo/semantics/openAccess |
| رقم الانضمام: |
edsbas.162585CE |
| قاعدة البيانات: |
BASE |