Academic Journal
Computerized Assessment of Wheezing in Children With Respiratory Syncytial Virus Bronchiolitis Before and After Hypertonic Saline Nebulization
| العنوان: | Computerized Assessment of Wheezing in Children With Respiratory Syncytial Virus Bronchiolitis Before and After Hypertonic Saline Nebulization |
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| المؤلفون: | Faber, Tina E, Kamps, Arvid Wa, Sjoerdsma, Machtelt H, Vermeulen, Stephanie, Veeger, Nic Jgm, Bont, Louis J |
| المصدر: | Faber , T E , Kamps , A W , Sjoerdsma , M H , Vermeulen , S , Veeger , N J & Bont , L J 2015 , ' Computerized Assessment of Wheezing in Children With Respiratory Syncytial Virus Bronchiolitis Before and After Hypertonic Saline Nebulization ' , Respiratory care , vol. 60 , no. 9 , pp. 1252-1256 . https://doi.org/10.4187/respcare.03754 |
| سنة النشر: | 2015 |
| المجموعة: | University of Groningen research database |
| مصطلحات موضوعية: | Acoustics, Auscultation/instrumentation, Bronchiolitis, Viral/complications, Child, Preschool, Diagnosis, Computer-Assisted, Female, Humans, Infant, Newborn, Male, Nebulizers and Vaporizers, Respiration, Respiratory Sounds/diagnosis, Respiratory Syncytial Virus Infections/complications, Respiratory Syncytial Virus, Human, Saline Solution, Hypertonic/administration & dosage, Severity of Illness Index, Symptom Assessment/methods |
| الوصف: | BACKGROUND: Studies suggest an effect of nebulized hypertonic saline solution on air-flow limitation in subjects with respiratory syncytial virus (RSV) bronchiolitis, but results are based on subjective scores of clinical severity and are not clear. In this observational study, we used a noninvasive computerized tool to quantify wheezing before and after nebulization with hypertonic saline in children admitted for RSV infection. METHODS: Twenty-seven children (≤ 24 months old) admitted to the pediatric ward of the Medical Center Leeuwarden with polymerase chain reaction-confirmed RSV bronchiolitis were included. Subjects were simultaneously assessed both clinically and by computerized acoustic monitoring before and 15 min after treatment with nebulized hypertonic saline solution. RESULTS: Clinical assessment, defined by the Respiratory Distress Assessment Instrument score, did not change after nebulization (n = 27, 5.0 vs 4.7, P = .17). Computerized acoustic monitoring showed no improvement in wheezing (n = 27, 3.4% vs 2.0%, P = .05) or inspiration/expiration ratio (0.85 vs 0.85, P = .93) after nebulization. CONCLUSIONS: Hypertonic saline nebulization does not improve air flow, as assessed by both clinical and computerized acoustic scores, in children admitted for RSV. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | https://research.rug.nl/en/publications/9f413ad0-3adf-4b92-9268-46c93c396775 |
| DOI: | 10.4187/respcare.03754 |
| الاتاحة: | https://hdl.handle.net/11370/9f413ad0-3adf-4b92-9268-46c93c396775 https://research.rug.nl/en/publications/9f413ad0-3adf-4b92-9268-46c93c396775 https://doi.org/10.4187/respcare.03754 https://pure.rug.nl/ws/files/77805648/1252.full.pdf |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.15FD2484 |
| قاعدة البيانات: | BASE |
| DOI: | 10.4187/respcare.03754 |
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