Academic Journal
Early detection of poor glycemic control in patients with diabetes mellitus in sub-Saharan Africa: a cohort study in Mozambique
| العنوان: | Early detection of poor glycemic control in patients with diabetes mellitus in sub-Saharan Africa: a cohort study in Mozambique |
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| المؤلفون: | Ciccacci F., Manto A., Morviducci L., Lanti F., Majid N., Agy M., Massango C., Orlando S., Guidotti G., Marazzi M. C. |
| المساهمون: | Ciccacci, F, Manto, A, Morviducci, L, Lanti, F, Majid, N, Agy, M, Massango, C, Orlando, S, Guidotti, G, Marazzi, Mc |
| بيانات النشر: | Makerere University, Medical School |
| سنة النشر: | 2022 |
| المجموعة: | Universitá degli Studi di Roma "Tor Vergata": ART - Archivio Istituzionale della Ricerca |
| مصطلحات موضوعية: | Diabetes Mellitus, Health Care, Non-Communicable Diseases, Settore MED/42 - IGIENE GENERALE E APPLICATA |
| الوصف: | Introduction: WHO estimates 422 million cases of diabetes mellitus worldwide. Mozambique has the second-highest mortality related to DM in the African region. Objectives of the present study are to provide data about a DM care service in Mozambique and to evaluate early outcomes of treatment. Methods: The new patients diagnosed with DM in a two-years period in a health centre in Maputo (Mozambique) were included in a retrospective cohort study. Fasting blood glucose (FBG), waist circumference (WC) and BMI were collected at baseline and after three months. Results: 188 patients were enrolled. Median BMI, WC and FBG at baseline were respectively 28 kg/m2(Inter Quartile Range [IQR]23.4-31.8), 98cm (IQR 87-105) and 209mg/dL (IQR 143-295). A non-pharmacological intervention was prescribed for six patients, while 182 patients received metformin 500 mg b.i.d. FBG was significantly reduced at control (226[±103.7]mg/dL vs 186[±93.2]mg/dL, p<0.000); however, glycemic control was reached in 74 patients (39.4%); not controlled patients changed regimen. Elderly patients had a higher glycemic control (adjusted Odds Ratio 2.50, 95% CI 1.11-5.06, p=0.002). Conclusion: Strategies for early detection of scarce glycemic control are feasible in Mozambique and could lead to prompt regimen switch; an invasive therapeutic approach could be preferable in selected cases to achieve control. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/37092081; info:eu-repo/semantics/altIdentifier/wos/WOS:000922074300015; volume:22; issue:4; firstpage:127; lastpage:132; numberofpages:6; journal:AFRICAN HEALTH SCIENCES; https://hdl.handle.net/2108/329211; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85145200503 |
| DOI: | 10.4314/ahs.v22i4.16 |
| الاتاحة: | https://hdl.handle.net/2108/329211 https://doi.org/10.4314/ahs.v22i4.16 |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.15FBFA49 |
| قاعدة البيانات: | BASE |
| DOI: | 10.4314/ahs.v22i4.16 |
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