Academic Journal
Fibrous biomaterials: Effect of textile topography on foreign body reaction
| العنوان: | Fibrous biomaterials: Effect of textile topography on foreign body reaction |
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| المؤلفون: | Girault, Elise, Biguenet, Florence, Eidenschenk, Antoinette, Dupuis, Dominique, Barbet, Romain, Heim, Frederic |
| المساهمون: | Laboratoire de Physique et Mécanique Textiles - LPMT - UR4365 (LPMT), Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Matériaux et Nanosciences Grand-Est (MNGE), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS) |
| المصدر: | ISSN: 1552-4973 ; EISSN: 1552-4981. |
| بيانات النشر: | HAL CCSD Wiley |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | [SPI.MECA]Engineering Sciences [physics]/Mechanics [physics.med-ph] |
| الوصف: | Foreign Body Reaction (FBR) is a critical issue to be addressed when polyethylene terephthalate (PET) textile implants are considered in the medical field to treat pathologies involving hernia repair, revascularization strategies in arterial disease, and aneurysm or heart valve replacement. The natural porosity of textile materials tends to induce exaggerated tissue ingrowth which may prevent the implants from remaining flexible. The purpose of this study is to assess the influence of the textile topography of various woven substrates on the wetting properties of these substrates and on their in vitro interaction with mesenchymal stem cells (MSC) at 24 and 72 hr. The tests were performed both at yarn and fabric level under forced wetting and ingrowth conditions in order to replicate the mechanisms going on in vivo under blood pressure. Results demonstrate that cell proliferation is influenced by the textile wetting properties, which can be tuned at yarn and fabric level. In particular, it is shown that a satin weave obtained from porous spun yarn limits cell proliferation due to the high porosity of the yarn and the limited saturation index of the weave. Yarn and fabric saturation seems to play a predominant role in cell proliferation on textile substrates. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | hal-03550263; https://hal.science/hal-03550263 |
| DOI: | 10.1002/jbm.b.34810 |
| الاتاحة: | https://hal.science/hal-03550263 https://doi.org/10.1002/jbm.b.34810 |
| رقم الانضمام: | edsbas.144254B9 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1002/jbm.b.34810 |
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