التفاصيل البيبلوغرافية
| العنوان: |
Structure based alignment and clustering of proteins (STRALCP) |
| المؤلفون: |
Zemla, Adam T., Zhou, Carol E., Smith, Jason R., Lam, Marisa W. |
| سنة النشر: |
2023 |
| المجموعة: |
SciTec Connect (Office of Scientific and Technical Information - OSTI, U.S. Department of Energy) |
| مصطلحات موضوعية: |
59 BASIC BIOLOGICAL SCIENCES |
| الوصف: |
Disclosed are computational methods of clustering a set of protein structures based on local and pair-wise global similarity values. Pair-wise local and global similarity values are generated based on pair-wise structural alignments for each protein in the set of protein structures. Initially, the protein structures are clustered based on pair-wise local similarity values. The protein structures are then clustered based on pair-wise global similarity values. For each given cluster both a representative structure and spans of conserved residues are identified. The representative protein structure is used to assign newly-solved protein structures to a group. The spans are used to characterize conservation and assign a "structural footprint" to the cluster. |
| نوع الوثيقة: |
other/unknown material |
| وصف الملف: |
application/pdf |
| اللغة: |
unknown |
| Relation: |
http://www.osti.gov/servlets/purl/1084076; https://www.osti.gov/biblio/1084076 |
| الاتاحة: |
http://www.osti.gov/servlets/purl/1084076
https://www.osti.gov/biblio/1084076 |
| رقم الانضمام: |
edsbas.13FD32A5 |
| قاعدة البيانات: |
BASE |