Academic Journal
Theoretical study of retinol, niacinamide and glycolic acid with halloysite clay mineral as active ingredients for topical skin care formulations
| العنوان: | Theoretical study of retinol, niacinamide and glycolic acid with halloysite clay mineral as active ingredients for topical skin care formulations |
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| المؤلفون: | Borrego Sánchez, Ana, Sainz-Díaz, C. Ignacio, Perioli, Luana, Viseras, César |
| المساهمون: | Ministerio de Economía, Industria y Competitividad (España), Junta de Andalucía |
| بيانات النشر: | Multidisciplinary Digital Publishing Institute |
| سنة النشر: | 2021 |
| المجموعة: | Digital.CSIC (Consejo Superior de Investigaciones Científicas / Spanish National Research Council) |
| مصطلحات موضوعية: | Halloysite, Retinol, Niacinamide, Glycolic acid, Adsorption, Molecular modeling |
| الوصف: | The adsorption of retinol, niacinamide and glycolic acid active ingredients on the internal surface of halloysite in an aqueous environment was explored at the molecular level by means of calculations based on quantum mechanics and force fields from empirical interatomic potentials. These active ingredients are stably adsorbed on the internal surface of halloysite forming hydrogen bonds between the hydrogen, oxygen and nitrogen atoms with the hydroxyl groups of the inner surface of the halloysite. In addition, electrostatic interaction between these active ingredients with the water molecules was observed. Therefore, the theoretical results indicate that the adsorption of these active principles is favourable in the halloysite nanotube, which allows directing future experimental investigations for the development and design of retinol, niacinamide and glycolic acid with halloysite nanotubes systems, which may be topical formulations for skincare. ; This research was funded by Spanish Ministerio de Economía, Industría y Competitividad, grant number PCIN2017-098, and by Regional Government Junta de Andalucía with FEDER European contribution, grant number P18-RT-3786. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | unknown |
| تدمد: | 1420-3049 |
| Relation: | #PLACEHOLDER_PARENT_METADATA_VALUE#; info:eu-repo/grantAgreement/MINECO//IPCIN2017-098; Publisher's version; http://dx.doi.org/10.3390/molecules26154392; Sí; Molecules 26 (2021); http://hdl.handle.net/10261/261937; http://dx.doi.org/10.13039/501100011011; http://dx.doi.org/10.13039/501100010198 |
| DOI: | 10.3390/molecules26154392 |
| DOI: | 10.13039/501100011011 |
| DOI: | 10.13039/501100010198 |
| الاتاحة: | http://hdl.handle.net/10261/261937 https://doi.org/10.3390/molecules26154392 https://doi.org/10.13039/501100011011 https://doi.org/10.13039/501100010198 |
| Rights: | open |
| رقم الانضمام: | edsbas.13D472FF |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 14203049 |
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| DOI: | 10.3390/molecules26154392 |