التفاصيل البيبلوغرافية
| العنوان: |
Fig. 3 in The Genome of the Blue Death-Feigning Beetle, Asbolus verrucosus Leconte, 1851 (Coleoptera: Tenebrionidae) |
| المؤلفون: |
Rider, S. Dean |
| المصدر: |
The Coleopterists Bulletin, 77(4), 481-500, (2023-12-21) |
| بيانات النشر: |
Zenodo |
| سنة النشر: |
2023 |
| المجموعة: |
Zenodo |
| مصطلحات موضوعية: |
Biodiversity, Taxonomy |
| الوصف: |
Fig. 3. Proposed death-feigning pathway genes and their normal functions. A) ATP is required for sustained muscle contractions used to maintain tonic immobility. ATP is generated in all cells; however, the fat body is where the majority of energy storage is considered to take place in the form of glycogen and triacylglycerol. Gyg2 initiates glycogen storage. Glucose may be transported to hemolymph or converted into trehalose. Trehalose is converted back to glucose after traveling through hemolymph and before entering target cells to be used in generating ATP. Triacylglycerol is catabolized by Lipase3 into long-chain fatty acids (LCFA) and diacylglycerol which can be transported to target cells, or diacylglycerol may be converted to glucose through a phosphoglycerate intermediate. Lipase in target cells catabolizes diacylglycerol into LCFA that undergo beta oxidation in the peroxisomes and mitochondria to form ATP. Pex12 is a peroxisomal membrane protein that participates in peroxisome biogenesis. B) Nif3L1 promotes stem cell differentiation into neurons. Dis3L2 is required to rebuild the neuromuscular junction (NMJ) during metamorphosis by regulating the expression of let-7 microRNAs in stem cells. Megf8 is required at the neuromuscular junction to promote its formation. Through the interaction of its PDZ domains with the C-termini of its partners, an InaD serves to anchor G-protein coupled receptors (GPCR) and Atp13A3. Signaling mediated by a kinin-like peptide through the GPCR may facilitate signals for acetylcholine release. The polyamines transported into the cytoplasm through Atp13A3 could block the function of ion channels (Ca, Na, BK, Kir, CNG, NMDA, and nAChr). Agrin promotes post-synaptic aggregation of nicotinic acetylcholine receptors (nAChR) which transduce signals for muscle contraction. Esyt2 shunts presynaptic calcium to the ER, reducing cytoplasmic calcium levels that would slow synaptic vesicle recycling. Perturbations of these proteins may attenuate fast excitatory signals at NMJ that depend on ... |
| نوع الوثيقة: |
other/unknown material |
| اللغة: |
unknown |
| Relation: |
https://doi.org/10.1649/0010-065X-77.4.481; lsid:urn:lsid:plazi.org:pub:FFC06C7840059A481B63477BAF15FFD5; https://zenodo.org/record/13243392; https://zenodo.org/communities/biosyslit; https://doi.org/10.5281/zenodo.13243397; https://doi.org/10.5281/zenodo.13243398; oai:zenodo.org:13243398 |
| DOI: |
10.5281/zenodo.13243398 |
| الاتاحة: |
https://doi.org/10.5281/zenodo.13243398 |
| Rights: |
info:eu-repo/semantics/openAccess ; License Not Specified |
| رقم الانضمام: |
edsbas.1396B0CE |
| قاعدة البيانات: |
BASE |