التفاصيل البيبلوغرافية
| العنوان: |
Table_1_Bleeding Risk Profile in Patients on Oral Anticoagulation Undergoing Percutaneous Coronary Interventions: A Prospective 24 Months Cohort Study.DOCX |
| المؤلفون: |
Sara Schukraft (6279599), Tibor Huwyler (11503921), Cindy Ottiger-Mankaka (11503924), Sonja Lehmann (11503927), Ezia Cook (11503930), Daphné Doomun (11503933), Ianis Doomun (11503936), Jean-Jacques Goy (95647), Jean-Christophe Stauffer (701035), Mario Togni (11503939), Diego Arroyo (3576839), Serban Puricel (6279623), Stéphane Cook (142410) |
| سنة النشر: |
2021 |
| المجموعة: |
Smithsonian Institution: Digital Repository |
| مصطلحات موضوعية: |
Cardiology, Cardiology (incl. Cardiovascular Diseases), Cardiorespiratory Medicine and Haematology not elsewhere classified, high bleeding risk, ACR-HBR criteria, percutaneous coronary intervention, oral anticoagulation, triple antithrombotic therapy |
| الوصف: |
Background: The Academic Research Consortium has identified a set of major and minor risk factors in order to standardize the definition of a high bleeding risk (ACR-HBR). Oral anticoagulation is a major criterion frequently observed. Aims: The objective of this study is to quantify the risk of bleeding in patients on oral anticoagulation with at least one additional major ACR-HBR criteria in the Cardio-Fribourg Registry. Methods: Between 2015 and 2017, consecutive patients undergoing percutaneous coronary intervention were prospectively included in the Cardio-Fribourg registry. The study population included patients with ongoing long-term oral anticoagulation (OAC) and planned to receive triple antithrombotic therapy. Patients were divided in two groups: patients on OAC with at least one additional major ACR-HBR criteria vs. patients on OAC without additional major ACR-HBR criteria. The primary endpoint was any bleeding during the 24-month follow-up. Secondary bleeding endpoint was defined as Bleeding Academic Research Classification (BARC) ≥3. Results: Follow-up was completed in 142 patients at high bleeding risk on OAC, of which 33 (23%) had at least one additional major ACR-HBR criteria. The rate of the primary endpoint was 55% in patients on OAC with at least one additional ACR-HBR criteria compared with 14% in patients on OAC without additional ACR-HBR criteria (hazard ratio, 3.88; 95%CI, 1.85–8.14; p < 0.01). Patients with additional major ACR-HBR criteria also experienced significantly higher rates of BARC ≥ 3 bleedings (39% at 24 months). Conclusion: The presence of at least one additional ACR-HBR criterion identifies patients on OAC who are at very high risk of bleeding after percutaneous coronary intervention. |
| نوع الوثيقة: |
dataset |
| اللغة: |
unknown |
| Relation: |
https://figshare.com/articles/dataset/Table_1_Bleeding_Risk_Profile_in_Patients_on_Oral_Anticoagulation_Undergoing_Percutaneous_Coronary_Interventions_A_Prospective_24_Months_Cohort_Study_DOCX/16703494 |
| DOI: |
10.3389/fcvm.2021.589426.s001 |
| الاتاحة: |
https://doi.org/10.3389/fcvm.2021.589426.s001 |
| Rights: |
CC BY 4.0 |
| رقم الانضمام: |
edsbas.11D6FFA6 |
| قاعدة البيانات: |
BASE |