Academic Journal
AMPK integrates metabolite and kinase-based immunometabolic control in macrophages
| العنوان: | AMPK integrates metabolite and kinase-based immunometabolic control in macrophages |
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| المؤلفون: | Phair, Iain, Nisr, Raid, Howden, Andrew, Sovakova, Magdalena, Alqurashi, Noor, Foretz, Marc, Lamont, Douglas, Viollet, Benoit, Rena, Graham |
| المساهمون: | University of Dundee, Institut Cochin (IC UM3 (UMR 8104 / U1016)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité) |
| المصدر: | ISSN: 2212-8778 ; Molecular metabolism ; https://hal.science/hal-04300956 ; Molecular metabolism, 2023, 68, pp.101661. ⟨10.1016/j.molmet.2022.101661⟩. |
| بيانات النشر: | HAL CCSD Elsevier |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | High-protein diet, Knock-out mice, Liver, Low-protein diet, Protein synthesis, Proteolysis, A769662, AMPK, Arginine, Cholesterol, Glucose, Immunometabolism, Itaconate, Macrophages, Metformin, Prostaglandins, MESH: AMP-Activated Protein Kinases, MESH: Macrophages, MESH: Succinates, MESH: Signal Transduction, MESH: Protein Serine-Threonine Kinases, MESH: Diet, Protein-Restricted, MESH: Postprandial Period, MESH: Mice, Inbred C57BL, MESH: Liver, MESH: Mammals, [SDV]Life Sciences [q-bio] |
| الوصف: | International audience ; Previous mechanistic studies on immunometabolism have focused on metabolite-based paradigms of regulation, such as itaconate. Here, we, demonstrate integration of metabolite and kinase-based immunometabolic control by AMP kinase. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/36586434; hal-04300956; https://hal.science/hal-04300956; https://hal.science/hal-04300956/document; https://hal.science/hal-04300956/file/1-s2.0-S2212877822002307-main.pdf; PUBMED: 36586434; PUBMEDCENTRAL: PMC9842865 |
| DOI: | 10.1016/j.molmet.2022.101661 |
| الاتاحة: | https://hal.science/hal-04300956 https://hal.science/hal-04300956/document https://hal.science/hal-04300956/file/1-s2.0-S2212877822002307-main.pdf https://doi.org/10.1016/j.molmet.2022.101661 |
| Rights: | info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.117E1C8D |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.molmet.2022.101661 |
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