Academic Journal
Clinical features and gene-and microRNA-expression patterns in adult acute leukemia patients with t(11;19)(q23;p13.1) and t(11;19)(q23;p13.3)
| العنوان: | Clinical features and gene-and microRNA-expression patterns in adult acute leukemia patients with t(11;19)(q23;p13.1) and t(11;19)(q23;p13.3) |
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| المؤلفون: | Bhatnagar, B., Blachly, J. S., Kohlschmidt, J., Eisfeld, A. K., VOLINIA, Stefano, Nicolet, D., Carroll, A. J., Block, A. W., Kolitz, J. E., Stone, R. M., Mrózek, K., Byrd, J. C., Bloomfield, C. D. |
| المساهمون: | Bhatnagar, B., Blachly, J. S., Kohlschmidt, J., Eisfeld, A. K., Volinia, Stefano, Nicolet, D., Carroll, A. J., Block, A. W., Kolitz, J. E., Stone, R. M., Mrózek, K., Byrd, J. C., Bloomfield, C. D. |
| سنة النشر: | 2016 |
| المجموعة: | Università degli Studi di Ferrara: CINECA IRIS |
| مصطلحات موضوعية: | Medicine (all), Hematology, Cancer Research, Anesthesiology and Pain Medicine |
| الوصف: | Translocations involving the KMT2A (MLL) gene, located at 11q23, and two different partner genes, ELL and MLLT1, located at 19p13.1 and 19p13.3, respectively, have been reported in both acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL).1, 2 However, there are limited data describing clinical and molecular differences between adult patients with t(11;19)(q23;p13.1) and those with t(11;19)(q23;p13.3). Neither the Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer3 nor large studies correlating chromosome abnormalities with clinical outcome4 distinguish the two types of t(11;19); instead they combine both into one cytogenetic group. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | STAMPA |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/26669971; info:eu-repo/semantics/altIdentifier/wos/WOS:000379504400017; volume:30; issue:7; firstpage:1586; lastpage:1589; numberofpages:4; journal:LEUKEMIA; http://hdl.handle.net/11392/2356332; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84954508527; https://www.nature.com/articles/leu2015345; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004206/pdf/nihms802629.pdf |
| DOI: | 10.1038/leu.2015.345 |
| الاتاحة: | http://hdl.handle.net/11392/2356332 https://doi.org/10.1038/leu.2015.345 https://www.nature.com/articles/leu2015345 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004206/pdf/nihms802629.pdf |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.11773B9B |
| قاعدة البيانات: | BASE |
| DOI: | 10.1038/leu.2015.345 |
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