Academic Journal
Comparison of chest computed tomography and 3-T magnetic resonance imaging results in patients with common variable immunodeficiency
| العنوان: | Comparison of chest computed tomography and 3-T magnetic resonance imaging results in patients with common variable immunodeficiency |
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| المؤلفون: | Çinkooğlu A., Bayraktaroğlu S., Tunakan Dalgıç C., Boğatekin G., Uysal F.E., Ardeniz Ö. |
| بيانات النشر: | SAGE Publications Inc. |
| سنة النشر: | 2022 |
| المجموعة: | Ege University Institutional Repository |
| مصطلحات موضوعية: | immunodeficiency, computed tomography, lung, Magnetic resonance imaging, Computerized tomography, Diagnosis, Computed tomography scan, Diagnostic performance, Follow up, Prospective study, Pulmonary infections, Slice thickness, T2 weighted |
| الوصف: | Background: Patients with common variable immunodeficiency (CVID) have an increased incidence of pulmonary infections and require frequent follow-up computed tomography (CT) scans. Purpose: To evaluate the diagnostic performance of 3-T magnetic resonance imaging (MRI) in patients with CVID. Material and Methods: In this prospective study, 3-T MRI was performed in 20 patients with CVID. The patients were imaged with CT and MRI scans on the same day. The MRI protocol included a T2-weighted HASTE sequence (TR=1400 ms, TE=95 ms, slice thickness (ST)=3 mm), T2-weighted BLADE sequence (TR=5379 ms, TE=100 ms, ST=3 mm), and 3D VIBE sequence (TR=3.9 ms, TE=1.32 ms, ST=3 mm). Mediastinal and parenchymal changes were compared. A modified Bhalla scoring system was used in the evaluation of CT and MRI scans. Results: A total of 17 (85%) patients had parenchymal abnormalities identified by CT or MRI. Similar findings were detected with CT and MRI in the assessment of the severity of bronchiectasis (P=0.083), bronchial wall thickening (P=0.157), and mucus plugging (P=0.250). Consolidations were detected with both modalities in all patients. There was excellent concordance between the two modalities in the evaluation of nodules >5 mm (nodule size 5–10 mm, P=0.317; nodule size >10?mm, P=1). However, MRI failed to detect most of the small nodules (5 mm). Conclusion: 3-T MRI detected mediastinal and parenchymal alterations in patients with CVID and provided findings that correlated well with CT. Despite a few limitations, MRI is a well-suited radiation-free technique for patients requiring longitudinal imaging. © The Foundation Acta Radiologica 2022. ; The author(s) disclosed receipt of the following financial support for the authorship, research, and publication of this Article: This work was supported by a grant (project no. TGA-2021-22601), provided by Ege University. ; Ege Üniversitesi |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 02841851 |
| Relation: | Acta Radiologica; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; https://hdl.handle.net/11454/79728; https://doi.org/10.1177/02841851221144249 |
| DOI: | 10.1177/02841851221144249 |
| الاتاحة: | https://hdl.handle.net/11454/79728 https://doi.org/10.1177/02841851221144249 |
| Rights: | none |
| رقم الانضمام: | edsbas.1123DE36 |
| قاعدة البيانات: | BASE |
| تدمد: | 02841851 |
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| DOI: | 10.1177/02841851221144249 |