Modeling of Proton Interaction with Organic Polymers: Implications for Cancer Therapy and Beyond

التفاصيل البيبلوغرافية
العنوان: Modeling of Proton Interaction with Organic Polymers: Implications for Cancer Therapy and Beyond
المؤلفون: Matias, F., Silva, T. F., Koval, N. E., Pereira, J. J. N., Antunes, P. C. G., Siqueira, P. T. D., Tabacniks, M. H., Yoriyaz, H., Shorto, J. M. B., Grande, P. L.
سنة النشر: 2024
المجموعة: Physics (Other)
مصطلحات موضوعية: Physics - Atomic Physics
الوصف: This comprehensive study delves into the intricate interplay between protons and organic polymers, offering insights into proton therapy in cancer treatment. Focusing on the influence of the spatial electron density distribution on stopping power estimates, we employed time-dependent density functional theory (TDDFT), coupled with the Penn method. Surprisingly, the assumption of electron density homogeneity in polymers is fundamentally flawed, resulting in an overestimation of stopping power values at energies below 2 MeV, approximately. Moreover, Bragg's rule application in specific compounds exhibited significant deviations from experimental data in the Bragg peak region, challenging established norms.
Comment: 8 pages, 7 figures, research article
نوع الوثيقة: Working Paper
URL الوصول: http://arxiv.org/abs/2401.02853
رقم الانضمام: edsarx.2401.02853
قاعدة البيانات: arXiv