Synthesis, reactions, and antiarrhythmic activities of some novel pyrimidines and pyridines fused with thiophene moiety
| العنوان: | Synthesis, reactions, and antiarrhythmic activities of some novel pyrimidines and pyridines fused with thiophene moiety |
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| المؤلفون: | AMR, Abdel-Galil El-Sayed, ABDEL-HAFEZ, Naglaa Abdel-Samei, MOHAMED, Salwa Fahem, ABDALLA, Mohamed Mostafa |
| المصدر: | Volume: 33, Issue: 3 421-432 Turkish Journal of Chemistry |
| بيانات النشر: | TÜBİTAK, 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Engineering, Mühendislik, Pyrimidine,pyrimidinethione,thiazolopyrimidine,antiarrhythmic activity |
| الوصف: | We report herein the synthesis and antiarrhythmic activities of some newly synthesized heterocyclic theino[2,3-c]pyrimidine and theino[2,3-c]pyridine derivatives fused with thiophene moiety. Initially the acute toxicity of the compounds was assayed via the determination of their LD50. The antiarrhythmic activities for the compounds were determined and all the tested compounds were found more potent than Procaine amide\textregistered and Lidocaine\textregistered as positive antiarrhythmic controls. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1300-0527 1303-6130 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=tubitakulakb::c8440c1becff056740930e9b03b4bf5a https://dergipark.org.tr/tr/pub/tbtkchem/issue/11904/142321 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.tubitakulakb..c8440c1becff056740930e9b03b4bf5a |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13000527 13036130 |
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