Serum and Peritoneal Fluid Levels of Vascular Endothelial Growth Factor in Women with Endometriosis
| العنوان: | Serum and Peritoneal Fluid Levels of Vascular Endothelial Growth Factor in Women with Endometriosis |
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| المؤلفون: | Kianpour, M., Nematbakhsh, M., Ahmadi, S. M., Jafarzadeh, M., Hajjarian, M., Pezeshki, Z., tahereh safari, Eshraghi-Jazi, F. |
| المصدر: | International Journal of Fertility and Sterility, Vol 7, Iss 2, Pp 96-99 (2013) Scopus-Elsevier International Journal of Fertility & Sterility |
| بيانات النشر: | Royan Institute (ACECR), Tehran, 2013. |
| سنة النشر: | 2013 |
| مصطلحات موضوعية: | lcsh:R5-920, Gynecology and Female Infertility, Cellular and Molecular Science, Vascular Endothelial Growth Factor, Endometriosis, Peritoneal Fluid, lcsh:Medicine (General), Research Article |
| الوصف: | Background: Endometriosis is known as one of the most common disease in women of reproductive age. Due to important role of vascular endothelial growth factor (VEGF) in neo-vascularization for the implantation of endometrial cell, and also presence of different studies reported VEGF level in the serum and peritoneal fluid (PF) in endometriosis patients, this study was designed to determine the serum and PF levels of VEGF in endometriosis patients, and to compare with normal subjects. Materials and Methods: In this descriptive study, 179 women subjected to laparoscopy for the evaluation of infertility or pelvic pain were allocated into the following two groups: group I: different types of endometriosis patients (n=90) and group II: non-endometriosis patients (n=89). The PF from pelvis and venous blood samples were obtained. The VEGF concentration of the serum and PF were measured using enzyme immunoassay kit and were compared using t test. Results: The level of VEGF in serum was significantly less than that in PF in both groups (p=0.00). However, endometriosis patients had significantly higher level of VEGF in peritoneal fluid than non-endometriosis patients (p=0.043). Conclusion: According to our findings, endometriosis is not associated with change in the level of circulating VEGF. |
| اللغة: | English |
| تدمد: | 2008-0778 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::fe79f788797a502757b51ca3b3dcbceb http://ijfs.ir/library/upload/article/af_32332432253265334264385543462372333443224-Kianpour-1.pdf |
| Rights: | OPEN |
| رقم الانضمام: | edsair.pmid.dedup....fe79f788797a502757b51ca3b3dcbceb |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20080778 |
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