Applicability of the Global Lung Initiative 2012 Reference Values for Spirometry for Longitudinal Data of Elderly Women
العنوان: | Applicability of the Global Lung Initiative 2012 Reference Values for Spirometry for Longitudinal Data of Elderly Women |
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المؤلفون: | Hüls, Anke, Krämer, Ursula, Stolz, Sabine, Hennig, Frauke, Hoffmann, Barbara, Ickstadt, Katja, Vierkötter, Andrea, Schikowski, Tamara |
المصدر: | PLoS ONE, Vol 11, Iss 6, p e0157569 (2016) PLOS ONE, 11(6):e0157569 PLoS ONE |
بيانات النشر: | Public Library of Science (PLoS), 2016. |
سنة النشر: | 2016 |
مصطلحات موضوعية: | Pulmonology, Physiology, Economics, Vital Capacity, Social Sciences, lcsh:Medicine, Pathology and Laboratory Medicine, Geographical Locations, Elderly, Signs and Symptoms, Health Economics, Diagnostic Medicine, Reference Values, Germany, Forced Expiratory Volume, Geriatrics, Bronchitis, ERS, European Respiratory Society, Coughing, HNSW, healthy (no asthma or chronic bronchitis ever diagnosed regarding to the questionnaire answered by the participants) never-smoking women, GLI, Global Lung Initiative, FVC, forced vital capacity, SALIA, Study on the influence of Air pollution on Lung function, ATS, American Thoracic Society, Health economics, FEV1, forced expiratory volume in 1 second, Inflammation and Aging, LLN, lower limit of normal, Respiratory physiology, Age groups, Medicine and Health Sciences, Humans, Respiratory Physiology, Longitudinal Studies, lcsh:Science, Lung, Aged, lcsh:R, Biology and Life Sciences, Middle Aged, respiratory system, respiratory tract diseases, Health Care, Europe, Cross-Sectional Studies, Social Class, Age Groups, Spirometry, People and Places, Population Groupings, Female, lcsh:Q, Physiological Processes, Research Article, circulatory and respiratory physiology |
الوصف: | BACKGROUND AND OBJECTIVES: Lung function depends nonlinearly on age and height, so that the use of age and height specific reference values is required. The widely used age and height specific GLI (Global Lung Initiative) z-scores derived from cross-sectional data, however, have not been proven for validity in an elderly population or for longitudinal data. Therefore, we aimed to test their validity in a population of elderly women followed prospectively for more than 20 years. METHODS: We used spirometric data (forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC) and FEV1/FVC) from the SALIA cohort of German women (baseline: 1985–1994 (aged 55 years), follow-up: 2008/2009 and 2012/2013). We calculated GLI-z-scores for baseline and follow-up examination separately (cross-sectional evaluation) and individual differences in z-scores between baseline and follow-up (longitudinal evaluation) for healthy never-smoking women. RESULTS: GLI reference values for FEV1, FVC and FEV1/FVC were cross-sectionally and longitudinally equivalent with our SALIA data. The mean change in z-scores between baseline and follow-up was 0.33 for FEV1, 0.38 for FVC and -0.10 for FEV1/FVC. CONCLUSIONS: In conclusion, GLI z-scores fit cross-sectionally and longitudinally with FEV1, FVC and FEV1/FVC measured in women from Germany which indicates that they can be used in longitudinal association analyses. |
اللغة: | English |
تدمد: | 1932-6203 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::906372f8851b110cb7e8a9d45adc491f http://europepmc.org/articles/PMC4910985?pdf=render |
Rights: | OPEN |
رقم الانضمام: | edsair.pmid.dedup....906372f8851b110cb7e8a9d45adc491f |
قاعدة البيانات: | OpenAIRE |
تدمد: | 19326203 |
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