Vitamins D3 and K2 may partially counterbalance the detrimental effects of pentosidine in ex vivo human osteoblasts
| العنوان: | Vitamins D3 and K2 may partially counterbalance the detrimental effects of pentosidine in ex vivo human osteoblasts |
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| المؤلفون: | Sanguineti, R., FIAMMETTA MONACELLI, Parodi, A., Furfaro, A. L., Borghi, R., Pacini, D., Pronzato, M. A., Odetti, P., Molfetta, L., Traverso, N. |
| المصدر: | Web of Science Scopus-Elsevier |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Cells, Messenger, Osteocalcin, Alkaline Phosphatase, Antigens, Neoplasm, Arginine, Bone Remodeling, Cells, Cultured, Cholecalciferol, Collagen Type I, Gene Expression Regulation, Humans, Lysine, Mitogen-Activated Protein Kinases, Osteoblasts, Osteogenesis, Osteoprotegerin, RANK Ligand, RNA, Messenger, Vitamin K 2, Antigens, Cultured, Collagen Type I, alpha 1 Chain, Neoplasm, RNA |
| الوصف: | Osteoporosis is a metabolic multifaceted disorder, characterized by insufficient bone strength. It has been recently shown that advanced glycation end products (AGEs) play a role in senile osteoporosis, through bone cell impairment and altered biomechanical properties. Pentosidine (PENT), a wellcharacterized AGE, is also considered a biomarker of bone fracture. Adequate responses to various hormones, such as 1,25-dihydroxyvitamin D |
| تدمد: | 0393-974X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6df8ac947c860cffcf771c2c2d44f4d4 https://pubmed.ncbi.nlm.nih.gov/27655488 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.pmid.dedup....6df8ac947c860cffcf771c2c2d44f4d4 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 0393974X |
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