Acute aortic regurgitation due to infective endocarditis
| العنوان: | Acute aortic regurgitation due to infective endocarditis |
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| المؤلفون: | Claudia M, Cortés, José H, Casabé, Roberto R, Favaloro, Héctor, Raffaelli, Eduardo, Dulbecco, José, Abud, Fabián, Salmo, Melina, Riesco, Milagros, Seijo, Eduardo, Guevara |
| المصدر: | Medicina (Buenos Aires), Vol 77, Iss 5, Pp 373-381 (2017) |
| بيانات النشر: | Fundación Revista Medicina, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | Male, lcsh:Immunologic diseases. Allergy, in-hospital mortality predictors, acute aortic regurgitation, infective endocarditis, Aortic Valve Insufficiency, lcsh:R, lcsh:Medicine, Endocarditis, Bacterial, Middle Aged, lcsh:Infectious and parasitic diseases, Echocardiography, Acute Disease, Humans, Female, lcsh:RC109-216, Hospital Mortality, Prospective Studies, lcsh:RC581-607 |
| الوصف: | Acute aortic regurgitation (AAR) due to infective endocarditis (IE) is a serious disease and usually requires surgical treatment. Our study aims to compare the clinical, echocardiographic, and microbiological characteristics as well as in-hospital outcome of patients with AAR according to the severity of heart failure (HF) and to evaluate predictors of in-hospital mortality in a tertiary centre. In a prospective analysis, we compared patients with NYHA functional class I-II HF (G1) vs. functional class III-IV HF (G2). From 06/92 to 07/16, 439 patients with IE were hospitalized; 86 presented AAR: (G1, 39: 45.4% y G2, 47: 54.7%). The G1 had higher prosthetic IE (43.6% vs. 17%, p 0.01). All G2 patients had dyspnoea vs. 30.8% of the G1 (p < 0.0001). There were no differences in clinical, echocardiographic and microbiological characteristics. Surgical treatment was indicated mainly due to infection extension or valvular dysfunction in G1 and HF in G2. In-hospital mortality was 15.4% vs. 27.7% (G1 and G2 respectively p NS). In multivariate analysis, health care-associated acquisition (p 0.001), negative blood cultures (p 0.004), and functional class III-IV HF (p 0.039) were in-hospital mortality predictors. One-fifth of the patients with EI had AAR. Half of them had severe HF which needed emergency surgery and the remaining needed surgery for extension of the infection and / or valvular dysfunction. Both groups remain to have high surgical and in-hospital mortality. Health care-associated acquisition, negative blood cultures and advanced HF were predictors of in-hospital mortality |
| اللغة: | English |
| تدمد: | 1669-9106 0025-7680 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::24520336b88fa3e345711e717fa10f7c http://www.medicinabuenosaires.com/PMID/29044013.pdf |
| Rights: | OPEN |
| رقم الانضمام: | edsair.pmid.dedup....24520336b88fa3e345711e717fa10f7c |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16699106 00257680 |
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