CD45RA

التفاصيل البيبلوغرافية
العنوان: CD45RA
المؤلفون: Efthymia, Kokkinou, Ram Vinay, Pandey, Luca, Mazzurana, Irene, Gutierrez-Perez, Christopher Andrew, Tibbitt, Whitney, Weigel, Tea, Soini, Anna, Carrasco, Anna, Rao, Maho, Nagasawa, Suzanne M, Bal, Mattias, Jangard, Danielle, Friberg, Ulrik, Lindforss, Caroline, Nordenvall, Malin, Ljunggren, Staffan, Haapaniemi, Åsa V, Keita, Johan, Söderholm, Charlotte, Hedin, Hergen, Spits, Yenan T, Bryceson, Jenny, Mjösberg
المصدر: Science immunology. 7(70)
سنة النشر: 2022
مصطلحات موضوعية: Inflammation, Killer Cells, Natural, Humans, Cell Differentiation, Lymphocyte Activation, Immunity, Innate
الوصف: Innate lymphoid cells (ILCs) are highly plastic and predominantly mucosal tissue-resident cells that contribute to both homeostasis and inflammation depending on the microenvironment. The discovery of naïve-like ILCs suggests an ILC differentiation process that is akin to naïve T cell differentiation. Delineating the mechanisms that underlie ILC differentiation in tissues is crucial for understanding ILC biology in health and disease. Here, we showed that tonsillar ILCs expressing CD45RA lacked proliferative activity, indicative of cellular quiescence. CD62L distinguished two subsets of CD45RA
تدمد: 2470-9468
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::f0bcc42983c0abd3d073ab1175f096ea
https://pubmed.ncbi.nlm.nih.gov/35427178
رقم الانضمام: edsair.pmid..........f0bcc42983c0abd3d073ab1175f096ea
قاعدة البيانات: OpenAIRE