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Nitroglycerin-Citrate-Ethanol Catheter Lock Solution Is Highly Effective for

التفاصيل البيبلوغرافية
العنوان: Nitroglycerin-Citrate-Ethanol Catheter Lock Solution Is Highly Effective for
المؤلفون: Nylev, Vargas-Cruz, Ruth A, Reitzel, Joel, Rosenblatt, Anne-Marie, Chaftari, Rita, Wilson Dib, Ray, Hachem, Dimitrios P, Kontoyiannis, Issam I, Raad
المصدر: Antimicrobial agents and chemotherapy. 63(7)
سنة النشر: 2019
مصطلحات موضوعية: Antifungal Agents, Catheters, Ethanol, macromolecular substances, biochemical phenomena, metabolism, and nutrition, bacterial infections and mycoses, Anidulafungin, Citric Acid, Nitroglycerin, Pharmaceutical Solutions, Caspofungin, Amphotericin B, Biofilms, Catheter-Related Infections, Micafungin, Experimental Therapeutics, Voriconazole, Fluconazole, Candida
الوصف: Candida auris poses emerging risks for causing severe central line-associated bloodstream infections. We tested in vitro the ability of antifungal lock solutions to rapidly eradicate C. auris biofilms. Liposomal amphotericin B, amphotericin B deoxycholate, fluconazole, voriconazole, micafungin, caspofungin, and anidulafungin failed to completely eradicate all 10 tested C. auris biofilms. Conversely, nitroglycerin-citrate-ethanol (NiCE) catheter lock solution completely eradicated all replicates for all of C. auris biofilms tested.
تدمد: 1098-6596
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::9330798ac38f548cf58b37a786cdb74b
https://pubmed.ncbi.nlm.nih.gov/31036689
Rights: OPEN
رقم الانضمام: edsair.pmid..........9330798ac38f548cf58b37a786cdb74b
قاعدة البيانات: OpenAIRE
الوصف
تدمد:10986596