[Adjuvant chemoradiotherapy in advanced gastric cancer: experience in 168 patients]

التفاصيل البيبلوغرافية
العنوان: [Adjuvant chemoradiotherapy in advanced gastric cancer: experience in 168 patients]
المؤلفون: Nicolás, Isa O, Moisés, Russo N, Hernán, López V
المصدر: Revista medica de Chile. 142(2)
سنة النشر: 2013
مصطلحات موضوعية: Adult, Male, Antimetabolites, Antineoplastic, Neoplasm, Residual, Leucovorin, Chemoradiotherapy, Adjuvant, Middle Aged, Prognosis, Disease-Free Survival, Young Adult, Treatment Outcome, Stomach Neoplasms, Lymphatic Metastasis, Vitamin B Complex, Humans, Female, Fluorouracil, Neoplasm Recurrence, Local, Aged, Neoplasm Staging, Retrospective Studies
الوصف: Gastric cancer is one of the most lethal tumors in the Chilean population.To report the results of adjuvant chemoradiotherapy in advanced gastric cancer.Review of medical records of patients with locoregionally advanced gastric cancer, subjected to a curative resection and treated with adjuvant chemoradiotherapy. The treatment was based on the INT 0116/SWOG protocol, which includes 5-fuorouracil as a single agent. Patients were followed for a median of 58 months.the records of 168 patients (99 men) treated between 2004 and 2011, were reviewed. Median survival was 41 months. Median lapses between surgery and onset of chemo and radiotherapy were 12 and 17 weeks, respectively. Overall three and five years survival was 53 and 41%, respectively. On multivariate analysis the factors associated with a lower survival were an antral location of the tumor, presence of signet ring cells and more than 15 involved lymph nodes.Three and five years survival of gastric cancer patients subjected to adjuvant chemoradiotherapy was 53 and 41% respectively. These results are similar to those reported elsewhere.
تدمد: 0717-6163
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::88e0ef05ecac0ceaea1c26245cfcd5b3
https://pubmed.ncbi.nlm.nih.gov/24953108
Rights: OPEN
رقم الانضمام: edsair.pmid..........88e0ef05ecac0ceaea1c26245cfcd5b3
قاعدة البيانات: OpenAIRE