A pregnancy of unknown location is a descriptive term that can be defined after performing trans vaginal ultrasound. This situation includes patients with a positive pregnancy test but with no evidence of intra or extra uterine pregnancy on transvaginal sonography.To discuss different aspects of management of women with pregnancy of unknown location.Review of the literature.Serum human chorionic gonadotrophin levels, progesterone levels and mathematical models are helpful in the prediction of final outcome of pregnancy: intra uterine pregnancy, ectopic pregnancy, spontaneous resolution or persistent pregnancy of unknown location. Active expectant management of asymptomatic women with a pregnancy of unknown location has been shown to be safe.Surgical intervention (diagnostic laparoscopy and uterine curettage) to diagnose the location of the pregnancy should be restrictive.