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Techniques for the generation of humanized mouse models for immuno-oncology

التفاصيل البيبلوغرافية
العنوان: Techniques for the generation of humanized mouse models for immuno-oncology
المؤلفون: Chun I, Yu, Florentina, Marches, Te-Chia, Wu, Jan, Martinek, Karolina, Palucka
المصدر: Methods in enzymology. 636
سنة النشر: 2020
مصطلحات موضوعية: Disease Models, Animal, Mice, Neoplasms, T-Lymphocytes, Tumor Microenvironment, Animals, Humans, Xenograft Model Antitumor Assays
الوصف: Mouse models of human cancer have been used extensively to circumvent the complexity in human patients. However, murine models often inadequately recapitulate the human cancer-immune interface partly due to important differences between mouse and human immune systems. Immunodeficient mice when transplanted with CD34
تدمد: 1557-7988
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::5f28e200a379c2026792e694b4dc317a
https://pubmed.ncbi.nlm.nih.gov/32178826
رقم الانضمام: edsair.pmid..........5f28e200a379c2026792e694b4dc317a
قاعدة البيانات: OpenAIRE
الوصف
تدمد:15577988