İmmobilizasyon Stresi ve Kronik Hafif Stres Modellerinin Dişi Sıçanlarda Depresyon Benzeri Davranışlar Üzerine Etkilerinin Kıyaslanması: 10 Günlük Stres Süresinin Değerlendirmesi
التفاصيل البيبلوغرافية
العنوان:
İmmobilizasyon Stresi ve Kronik Hafif Stres Modellerinin Dişi Sıçanlarda Depresyon Benzeri Davranışlar Üzerine Etkilerinin Kıyaslanması: 10 Günlük Stres Süresinin Değerlendirmesi
Objective: This study was designed to compare the depression-related behavior-inducing potentials of 10-day immobilization stress and chronic mild stress in adult female rats. Materials and Methods: Adult Wistar rats were randomly divided into three groups (n=10) as control, immobilization stress (45 minutes per day) and chronic mild stress. Both stress protocols were applied for a period of 10 days. Behavioral tests were performed when the rats were in diestrus. Results: In the forced swimming test, immobility behavior in the immobilization stress group and chronic mild stress group was significantly higher than the control group (P