Background: The bachelor's thesis deals with the assessment of the long term health- related the quality of life (HRQOL) in children up 2 to 8 years of age following burn inury by The Brisbane Burn Scar Impact Profile (BBSIP) questionnaire in the Czech Republic. Objectives: The aim of the theoretical part of this thesis was to provide a review of the literature and individual studies about HRQOL in children following burn injury and its context. The aim of the empirical part was to assess the influence of individual socio- demographic and clinical determinants on the HRQOL in these patients, identify, which of these variables most predict the HRQOL and implicate these findings into the context of nursing practice regarding comprehensive care for pediatric patients with burns. In this study we also examined the psychometric properties of the czech version of the BBSIP questionnaire on a sample of pediatric patients in the Czech Republic. Methods: The study population comprised n = 1221 children aged up 2 to 8 years, who were hospitalized at the Department of Burn Medicine, 3rd Medical Faculty, Charles University and the Královské Vinohrady University Hospital in the period 2016-2021 and met inclusive and exclusive criteria. A set of BBSIP, POSAS and PedsQL questionnaires was sent to all caregivers...