Influence of rGO on the cristallization kinetics, cytoxicity, electrical and mechanical properties of PLCL scaffolds
| العنوان: | Influence of rGO on the cristallization kinetics, cytoxicity, electrical and mechanical properties of PLCL scaffolds |
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| المؤلفون: | Díaz, Esperanza, León, Joseba, Murillo-Marrodán, Alberto, Ribeiro, Sylvie Oliveira, Lanceros-Méndez, S. |
| المساهمون: | Universidade do Minho |
| بيانات النشر: | MDPI, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Scaffolds, Science & Technology, rGO, Cytotoxicity, Electrical properties, Mechanical properties, PLCL, PLCL/rGO, Crystallization |
| الوصف: | Biodegradable scaffolds of poly (L-lactide-co-ε-caprolactone) (PLCL) and reduced graphene oxide (rGO) were prepared by TIPS (thermally induced phase separation). The nonisothermal cold crystallization kinetics were investigated by differential scanning calorimetry (DSC) with various cooling rates. The experimental values indicate that nonisothermal crystallization improves with cooling rate, but the increasing rGO concentration delays crystallization at higher temperatures. The activation energies were calculated by the Kissinger equation; the values were very similar for PLCL and for its compounds with rGO. The electrical conductivity measurements show that the addition of rGO leads to a rapid transition from insulating to conductive scaffolds with a percolation value of ≈0.4 w/w. Mechanical compression tests show that the addition of rGO improves the mechanical properties of porous substrates. In addition, it is an anisotropic material, especially at compositions of 1% w/w of rGO. All of the samples with different rGO content up to 1% are cytotoxic for C2C12 myoblast cells. This work was supported by the University of The Basque Center. The authors acknowledge funding by Spanish State Research Agency (AEI) and the European Regional Development Fund (ERFD) through the project PID2019-106099RB-C43/AEI/10.13039/501100011033 and from the Basque Government Industry Departments under the ELKARTEK program. This work has been also supported by FCT-Fundacao para a Ciencia e Tecnologia (FCT) under the scope of the strategic funding of UID/FIS/04650/2020 and UIDB/04469/2020 units and project PTDC/BTM-MAT/28237/2017. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=od_______307::4bbcba173e0520f309a94c1eed92e06c https://hdl.handle.net/1822/81761 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.od.......307..4bbcba173e0520f309a94c1eed92e06c |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |