Sugar-sweetened beverage, artificially sweetened beverage and sugar intake and colorectal cancer survival
العنوان: | Sugar-sweetened beverage, artificially sweetened beverage and sugar intake and colorectal cancer survival |
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المؤلفون: | Emilie S Zoltick, Kimmie Ng, Stephanie A. Smith-Warner, Jeffrey A. Meyerhardt, Andrew T. Chan, Meir J. Stampfer, Chen Yuan, Molin Wang, Shuji Ogino, Charles S. Fuchs, Kana Wu, Edward Giovannucci |
المصدر: | Br J Cancer |
بيانات النشر: | Springer Science and Business Media LLC, 2021. |
سنة النشر: | 2021 |
مصطلحات موضوعية: | Adult, Male, Cancer Research, medicine.medical_specialty, Colorectal cancer, Article, chemistry.chemical_compound, Sugar intake, Cause of Death, Internal medicine, medicine, Humans, Prospective Studies, Sugar, Aged, Neoplasm Staging, Sugar-Sweetened Beverages, Health professionals, business.industry, Artificially Sweetened Beverages, Hazard ratio, Fructose, Middle Aged, medicine.disease, digestive system diseases, Confidence interval, Oncology, chemistry, Female, Fruit juice, Colorectal Neoplasms, Sugars, business |
الوصف: | BACKGROUND: The influence of a high sugar diet on colorectal cancer (CRC) survival is unclear. METHODS: Among 1463 stage I–III CRC patients from the Nurses’ Health Study and Health Professionals Follow-up Study, we estimated hazard ratios (HRs) and 95% confidence intervals (CIs) for CRC-specific and all-cause mortality in relation to intake of post-diagnosis sugar-sweetened beverages (SSB), artificially sweetened beverages (ASB), fruit juice, fructose and other sugars. RESULTS: Over a median 8.0 years, 781 cases died (173 CRC-specific deaths). Multivariable-adjusted HRs for post-diagnosis intake and CRC-specific mortality were 1.21 (95% CI: 0.87–1.68) per 1 serving SSBs per day (serving/day) and 1.24 (95% CI: 0.95–1.63) per 20 grams fructose per day. Significant positive associations for CRC-specific mortality were primarily observed ≤5 years from diagnosis (HR per 1 serving/day of SSBs = 1.59, 95% CI: 1.06–2.38). Significant inverse associations were observed between ASBs and CRC-specific and all-cause mortality (HR for ≥5 versus |
تدمد: | 1532-1827 0007-0920 |
DOI: | 10.1038/s41416-021-01487-7 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffd26087b1a64812a3d17230919b946a https://doi.org/10.1038/s41416-021-01487-7 |
Rights: | OPEN |
رقم الانضمام: | edsair.doi.dedup.....ffd26087b1a64812a3d17230919b946a |
قاعدة البيانات: | OpenAIRE |
تدمد: | 15321827 00070920 |
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DOI: | 10.1038/s41416-021-01487-7 |