Biomimetic catalysis of an organophosphate by molecularly surface imprinted polymers
| العنوان: | Biomimetic catalysis of an organophosphate by molecularly surface imprinted polymers |
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| المؤلفون: | Hayrettin Türk, Arzu Ersöz, Murat Erdem, Rıdvan Say, Adil Denizli |
| المساهمون: | Anadolu Üniversitesi, Fen Fakültesi, Fizik Bölümü, Say, Rıdvan, Ersöz, Arzu, Türk, Hayrettin |
| المصدر: | Applied Catalysis A: General. 286:221-225 |
| بيانات النشر: | Elsevier BV, 2005. |
| سنة النشر: | 2005 |
| مصطلحات موضوعية: | chemistry.chemical_classification, Enzyme Analogue, Paraoxon, Process Chemistry and Technology, Metal ions in aqueous solution, Biomimetic Catalysis, Polymer, Heterogeneous catalysis, Catalysis, Mip, Molecular Imprinting, Nerve Agent, chemistry.chemical_compound, Monomer, chemistry, medicine, Organic chemistry, Chelation, Detoxification, Molecular imprinting, medicine.drug, Nuclear chemistry |
| الوصف: | WOS: 000229819400008 A synthetic polymer selective for paraoxon was prepared by a molecular surface imprinting technique. We have combined molecular imprinting with the ability of histidine to chelate metal ions to create active centrum of phosphotriesterase on microbead surfaces. For this purpose, methacryloyl-histidine-copper(II) [MAH-Cu(II)] and methacryloyl-histidine-copper(II)-paraoxon [MAH-Cu(II)-paraoxon] metal chelating monomers were synthesized; paraoxon imprinted polymers were produced and the binding characteristics of the polymers were evaluated. The optimum pH was determined applying different pH values and the hydrolytic activity of phosphotriesterase was evaluated in the framework of Micheaelis-Menten kinetics. In addition, the values of maximal rate: V. (4.58 x 10(-2) mu M/min) and Micheaelis-Menten constant, K-m (1.28 x 10(-3) M), were obtained from Lineweaver-Burk plots for the imprinted polymeric catalyst |
| وصف الملف: | application/pdf |
| تدمد: | 0926-860X |
| DOI: | 10.1016/j.apcata.2005.03.015 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcebba61046a7a886fdd6de844f146f2 https://doi.org/10.1016/j.apcata.2005.03.015 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....fcebba61046a7a886fdd6de844f146f2 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 0926860X |
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| DOI: | 10.1016/j.apcata.2005.03.015 |