Genomic analysis of the population structure in horses of the Brazilian Mangalarga Marchador breed
| العنوان: | Genomic analysis of the population structure in horses of the Brazilian Mangalarga Marchador breed |
|---|---|
| المؤلفون: | Guilherme Luis Pereira, Rogério Abdallah Curi, Júlio Cesar de Carvalho Balieiro, Fernando de Oliveira Bussiman, Bruna Aparecida dos Santos, Victória R. Paschoal, Sérgio M. de Souza Júnior, Luis Artur Loyola Chardulo |
| المساهمون: | Universidade Estadual Paulista (Unesp), Universidade de São Paulo (USP) |
| المصدر: | Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | 0301 basic medicine, Veterinary medicine, Linkage disequilibrium, Effective size, Population, Population structure, SNP, Beef cattle, Biology, 03 medical and health sciences, education, education.field_of_study, General Veterinary, 0402 animal and dairy science, Mangalarga, 04 agricultural and veterinary sciences, biology.organism_classification, 040201 dairy & animal science, GENÉTICA ANIMAL, Breed, SNP genotyping, 030104 developmental biology, Animal Science and Zoology |
| الوصف: | Made available in DSpace on 2019-10-06T16:47:52Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-11-01 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) The Mangalarga Marchador is the Brazilian saddle horse. It has two characteristic gaits, marcha batida and marcha picada, that provide greater comfort to the rider during cavalcade and work. This horse breed is mainly used for work on beef cattle farms and different modalities of equestrian sports. The objective of this study was to characterize the linkage disequilibrium (LD), calculated by r², of Brazilian Mangalarga Marchador horses raised in Brazil using large-scale SNP genotyping. We also investigated the effective size (Ne) of the population, as well as its structure and relationships. A total of 240 Mangalarga Marchador horses of both sexes, registered with the Brazilian breeders association (ABCCMM), were used. The number of informative SNPs was 377,308. Principal component analysis showed that Mangalarga Marchador horses of the two different gait types belong to the same population, i.e., these groups did not segregate significantly within the breed. This finding should be taken into consideration in genetic population studies. The estimated genomic r² was 0.096 ± 0.166. The LD declined considerably at distances greater than 15 and 20 kb, with values lower than 0.3 and 0.2, respectively. The current Ne was 99 animals. There was a marked reduction in this parameter when the estimated Ne of 16 generations ago was considered, which was 650 animals. These results may be linked to a broad and partially open genetic base and to increasing selection pressures in the breed. Finally, we observed defined population substructures that were more related to the breed's important sires rather than to the type of gait. Department of Animal Science College of Agriculture and Veterinary Science São Paulo State University (FCAV/UNESP) Department of Animal Breeding and Nutrition College of Veterinary and Animal Science São Paulo State University (FMVZ/UNESP) Department of Animal Science College of Animal Science and Food Engineering University of São Paulo (FZEA/USP) Department of Animal Nutrition and Production College of Veterinary Medicine and Animal Science University of São Paulo (FMVZ/USP) Department of Animal Science College of Agriculture and Veterinary Science São Paulo State University (FCAV/UNESP) Department of Animal Breeding and Nutrition College of Veterinary and Animal Science São Paulo State University (FMVZ/UNESP) CAPES: 001 FAPESP: 2016/19081-9 |
| اللغة: | English |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbe32aff9bbad12a4a2af72e83887458 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....fbe32aff9bbad12a4a2af72e83887458 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |