Synthetic biology approaches to actinomycete strain improvement
| العنوان: | Synthetic biology approaches to actinomycete strain improvement |
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| المؤلفون: | Marianna Iorio, Erik K. R. Hanko, Alessandro Filisetti, Emmanuele Severi, Dominic R. Whittall, Rainer Breitling, Gregor Kosec, Michelle Rudden, Kamila Schmidt, Rosario Pérez Redondo, Lucija Slemc, Eriko Takano, Davide De Lucrezia, Antonio Rodríguez García, Olga Genilloud, Stefano Donadio, Gavin H. Thomas, Hrvoje Petković, Fernando Reyes, Francesco Del Carratore, Martina Avbelj, Oksana Bilyk |
| المصدر: | FEMS microbiology letters, vol. 368, no. 10, fnab060, 2021. FEMS Microbiology Letters Breitling, R, Avbelj, M, Bilyk, O, Del Carratore, F, Filisetti, A, Hanko, E K R, Iorio, M, Redondo, R P, Reyes, F, Rudden, M, Severi, E, Slemc, L, Schmidt, K, Whittall, D R, Donadio, S, García, A R, Genilloud, O, Kosec, G, De Lucrezia, D, Petković, H, Thomas, G & Takano, E 2021, ' Synthetic biology approaches to actinomycete strain improvement ', FEMS microbiology letters . https://doi.org/10.1093/femsle/fnab060 |
| مصطلحات موضوعية: | Mini Review, aktinomicete, Computational biology, Microbiology, Streptomyces, Actinobacteria, Mini review, Industrial Microbiology, 03 medical and health sciences, Synthetic biology, Biotechnology and Synthetic Biology, Manchester Institute of Biotechnology, Genetics, biosinteza, udc:602.3:579.873, Molecular Biology, 030304 developmental biology, AcademicSubjects/SCI01150, 0303 health sciences, biology, 030306 microbiology, Strain (biology), actinobacteria, ResearchInstitutes_Networks_Beacons/manchester_institute_of_biotechnology, biology.organism_classification, Metabolic Engineering, actinomycete, Synthetic Biology, Minireview, ComputingMethodologies_GENERAL, synthetic biology, biosynthesis, biotechnology |
| الوصف: | Their biochemical versatility and biotechnological importance make actinomycete bacteria attractive targets for ambitious genetic engineering using the toolkit of synthetic biology. But their complex biology also poses unique challenges. This mini review discusses some of the recent advances in synthetic biology approaches from an actinomycete perspective and presents examples of their application to the rational improvement of industrially relevant strains. Recent advances in synthetic biology driven engineering of the actinomycetes for the production of valuable drug compounds. |
| وصف الملف: | application/pdf; text/url |
| اللغة: | English |
| تدمد: | 1574-6968 0378-1097 |
| DOI: | 10.1093/femsle/fnab060 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb645ae558cf2eca30d066e8dd881d2d |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....fb645ae558cf2eca30d066e8dd881d2d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15746968 03781097 |
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| DOI: | 10.1093/femsle/fnab060 |