Clinical presentations of erosive esophagitis found at endoscopy in neurologically impaired children: a historical study

التفاصيل البيبلوغرافية
العنوان: Clinical presentations of erosive esophagitis found at endoscopy in neurologically impaired children: a historical study
المؤلفون: Joseph D. Edwards III, Parker Giroux, Kirby Keith, Samuel B. Jameson, Michael Nowicki, Sandra M. Camacho
المصدر: Annals of palliative medicine.
سنة النشر: 2022
مصطلحات موضوعية: Advanced and Specialized Nursing, Anesthesiology and Pain Medicine
الوصف: Data is lacking as to the clinical presentation of erosive esophagitis (EE) in neurologically impaired children compared to non-neurologically impaired children (non-NIC). To determinate the clinical presentation, associations, management, and outcomes of EE in neurologically impaired children compared to children without neurologic impairment.Retrospective chart review of all esophagogastroduodenoscopies performed in pediatric patients at the University of Mississippi Medical Center from 1998 to 2020 with the diagnosis of EE. Fisher's exact test was used to compare results from neurologically impaired children group and non-NIC. A probability0.05 was considered statistically significant.Forty-seven patients were diagnosed with EE and met study criteria. Twenty-six patients were neurologically impaired children, and 21 were non- neurologically impaired children. No significant difference was seen between age at diagnosis, sex, or hematologic markers of anemia. The most common indication for esophagogastroduodenoscopies in neurologically impaired children was hematemesis (65.4%), whereas abdominal pain (33.3%) was the most common in non-NIC. Neurologically impaired children were more likely to be treated with acid-blockade. Nine neurologically impaired children had gastrostomy tubes prior to diagnosis as opposed to 0 non-neurologically impaired children. After diagnosis, 8 neurologically impaired children underwent gastrostomy tube placement compared to 0 non-neurologically impaired children, and fundoplication was performed in 11 neurologically impaired children as compared to 1 non-NIC. The sensitivity of fecal occult blood test for detecting EE was higher for neurologically impaired children (91.7%) than for non-NIC (33.3%).EE in neurologically impaired children presents differently than in non-neurologically impaired children with blood loss being the most common presentation in neurologically impaired children. Neurologically impaired children are more likely to be treated with acid-blockade prior to diagnosis, likely due to heightened risk for gastroesophageal reflux disease (GERD). Additionally, they are more likely to undergo surgical management of EE than non- neurologically impaired children.
تدمد: 2224-5839
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9db240de51cf639e12ced389337b38e
https://pubmed.ncbi.nlm.nih.gov/36571169
رقم الانضمام: edsair.doi.dedup.....f9db240de51cf639e12ced389337b38e
قاعدة البيانات: OpenAIRE