Bone mineral density at diagnosis determines fracture rate in children with acute lymphoblastic leukemia treated according to the DCOG-ALL9 protocol
| العنوان: | Bone mineral density at diagnosis determines fracture rate in children with acute lymphoblastic leukemia treated according to the DCOG-ALL9 protocol |
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| المؤلفون: | Anjo J.P. Veerman, Wim C. J. Hop, Jan C. Roos, Jan A. Leeuw, Inge M. van der Sluis, Wouter J.W. Kollen, Jos P.M. Bökkerink, Mariël L. te Winkel, Rob Pieters, Marrie C. A. Bruin, Hester A. de Groot-Kruseman, Marry M. van den Heuvel-Eibrink |
| المساهمون: | Pediatrics, Epidemiology, Hematology, Radiology and nuclear medicine, Pediatric surgery, CCA - Innovative therapy |
| المصدر: | Bone, 59, 223-228. Elsevier Inc. Bone, 59, 223-228. ELSEVIER SCIENCE INC Bone, 59, 223-8 Bone, 59, pp. 223-8 BONE, 59, 223-228 te Winkel, M L, Pieters, R, Hop, W C J, Roos, J C, Bokkerink, J P M, Leeuw, J A, de Bruin, M C A, Kollen, W J W, Veerman, A J P, de Groot-Kruseman, H A, van der Sluis, I M & van den Heuvel-Eibrink, M M 2014, ' Bone mineral density at diagnosis determines fracture rate in children with acute lymphoblastic leukemia treated according to the DCOG-ALL9 protocol ', Bone, vol. 59, pp. 223-228 . https://doi.org/10.1016/j.bone.2013.11.017 |
| بيانات النشر: | ELSEVIER SCIENCE INC, 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Childhood acute lymphoblastic leukemia, Histology, Multivariate analysis, BODY-COMPOSITION, Bone density, Physiology, Endocrinology, Diabetes and Metabolism, Lymphoblastic Leukemia, Osteoporosis, Lumbar vertebrae, Rare cancers Radboud Institute for Molecular Life Sciences [Radboudumc 9], MASS, Fractures, Bone, MORBIDITY, Bone Density, Risk Factors, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Bone mineral density, Humans, Child, Childhood Acute Lymphoblastic Leukemia, Netherlands, Bone mineral, Lumbar Vertebrae, business.industry, Incidence, Incidence (epidemiology), X-RAY ABSORPTIOMETRY, Precursor Cell Lymphoblastic Leukemia-Lymphoma, medicine.disease, Surgery, medicine.anatomical_structure, Multivariate Analysis, Linear Models, T-CELLS, Female, Steroids, business, Fractures |
| الوصف: | Item does not contain fulltext PURPOSE: To elucidate incidence and risk factors of bone mineral density and fracture risk in children with Acute Lymphoblastic Leukemia (ALL). METHODS: Prospectively, cumulative fracture incidence, calculated from diagnosis until one year after cessation of treatment, was assessed in 672 patients. This fracture incidence was compared between subgroups of treatment stratification and age subgroups (Log-Rank test). Serial measurements of bone mineral density of the lumbar spine (BMDLS) were performed in 399 ALL patients using dual energy X-ray absorptiometry. We evaluated risk factors for a low BMD (multivariate regression analysis). Osteoporosis was defined as a BMDLS |
| اللغة: | English |
| تدمد: | 8756-3282 |
| DOI: | 10.1016/j.bone.2013.11.017 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f855003ca6f232559043df8bd462ade4 https://doi.org/10.1016/j.bone.2013.11.017 |
| Rights: | RESTRICTED |
| رقم الانضمام: | edsair.doi.dedup.....f855003ca6f232559043df8bd462ade4 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 87563282 |
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| DOI: | 10.1016/j.bone.2013.11.017 |