Malignant Perivascular Epitheloid Cell Tumor with an Unusual Immunophenotype in a Ten-Year-Old Child
| العنوان: | Malignant Perivascular Epitheloid Cell Tumor with an Unusual Immunophenotype in a Ten-Year-Old Child |
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| المؤلفون: | Nives Jonjić, Irena Seili-Bekafigo, Nedeljka Glavan, Ita Hadzisejdic, Jelena Roganović |
| المصدر: | Fetal and Pediatric Pathology Volume 38 Issue 6 |
| بيانات النشر: | Informa UK Limited, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | 0301 basic medicine, Pathology, medicine.medical_specialty, pediatric PEComa, Perivascular Epithelioid Cell Neoplasms, Cell, Soft Tissue Neoplasms, 030105 genetics & heredity, Immunophenotyping, Pathology and Forensic Medicine, 03 medical and health sciences, 0302 clinical medicine, Biomarkers, Tumor, medicine, Humans, PEComa, malignant perivascular epitheloid cell tumor, Child, 030219 obstetrics & reproductive medicine, business.industry, Mesenchymal stem cell, BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Pathology, Sarcoma, General Medicine, Immunohistochemistry, BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Patologija, medicine.anatomical_structure, Pediatrics, Perinatology and Child Health, Female, Cell tumor, business |
| الوصف: | Introduction: Perivascular epitheloid cell tumors (PEComa) represent a group of usually benign mesenchymal neoplasms. Malignant variants are usually found only in adults.Case: We present a 10-year-old girl with infraclavicular malignant PEComa, negative for HMB-45 and Melan A but focally positive for MITF.Conclusion: To the best of our knowledge, no malignant variant of PEComa has been described in soft tissue in a child. Generally, PEComas are immunoreactive for HMB-45 and/or Melan A while our case was negative for both. Further studies are necessary to elucidate the significance of this immunohistochemical finding. |
| وصف الملف: | application/pdf |
| تدمد: | 1551-3823 1551-3815 |
| DOI: | 10.1080/15513815.2019.1604923 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7f8f48cbd308bba5478b2710706c27b https://doi.org/10.1080/15513815.2019.1604923 |
| Rights: | RESTRICTED |
| رقم الانضمام: | edsair.doi.dedup.....f7f8f48cbd308bba5478b2710706c27b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15513823 15513815 |
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| DOI: | 10.1080/15513815.2019.1604923 |