Metathetic sulfur transfer mediated by N-(2-aminophenyl)-4-methyl-thiazolin-2-thione derivatives: a route to diversely substituted S-alkylcarbamothioates
| العنوان: | Metathetic sulfur transfer mediated by N-(2-aminophenyl)-4-methyl-thiazolin-2-thione derivatives: a route to diversely substituted S-alkylcarbamothioates |
|---|---|
| المؤلفون: | Nicolas Vanthuyne, Federico Andreoli, Mohammed Amine Mehdid, Abdallah Larbi Doukara, Christian Roussel, Ayada Djafri |
| المساهمون: | Institut des Sciences Moléculaires de Marseille (ISM2), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)-École Centrale de Marseille (ECM)-Institut de Chimie du CNRS (INC), Centre National de la Recherche Scientifique (CNRS)-École Centrale de Marseille (ECM)-Aix Marseille Université (AMU), Aix Marseille Université (AMU)-École Centrale de Marseille (ECM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS) |
| المصدر: | Tetrahedron Tetrahedron, Elsevier, 2010, 66 (10), pp.1852-1858. ⟨10.1016/j.tet.2010.01.020⟩ Tetrahedron, 2010, 66 (10), pp.1852-1858. ⟨10.1016/j.tet.2010.01.020⟩ |
| بيانات النشر: | HAL CCSD, 2010. |
| سنة النشر: | 2010 |
| مصطلحات موضوعية: | chemistry.chemical_classification, Benzimidazole, Base (chemistry), 010405 organic chemistry, Organic Chemistry, chemistry.chemical_element, Alkylation, 010402 general chemistry, 01 natural sciences, Biochemistry, Medicinal chemistry, Chemical synthesis, Sulfur, Nitrogen, 0104 chemical sciences, chemistry.chemical_compound, chemistry, Drug Discovery, Urea, [CHIM]Chemical Sciences, After treatment, ComputingMilieux_MISCELLANEOUS |
| الوصف: | A new route to S-alkylcarbamothioates is disclosed. In a first step, N-(2-aminophenyl)-4-methyl-thiazolin-2-thione is transformed into a mono- or disubstituted urea at nitrogen, and then in a second step, alkylated at sulfur. The resulting salts, after treatment with a base, gave S-alkylcarbamothioates in high isolated yields together with 3-methyl[1,3]thiazolo[3,2-a]benzimidazole under very mild conditions. |
| اللغة: | English |
| تدمد: | 0040-4020 |
| DOI: | 10.1016/j.tet.2010.01.020⟩ |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6e96536f4e0e0dae490f99e4ee36bcc https://hal.archives-ouvertes.fr/hal-02517500 |
| Rights: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....f6e96536f4e0e0dae490f99e4ee36bcc |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 00404020 |
|---|---|
| DOI: | 10.1016/j.tet.2010.01.020⟩ |