COVID-19 Manifesting as Renal Allograft Dysfunction, Acute Pancreatitis, and Thrombotic Microangiopathy: A Case Report
| العنوان: | COVID-19 Manifesting as Renal Allograft Dysfunction, Acute Pancreatitis, and Thrombotic Microangiopathy: A Case Report |
|---|---|
| المؤلفون: | Yihung Huang, Muna Alnimri, Tiana Jespersen Nizamic, Ling Xin Chen, Mingyu Cheng, Kuang-Yu Jen |
| المصدر: | Transplantation proceedings, vol 53, iss 4 Transplantation Proceedings |
| بيانات النشر: | eScholarship, University of California, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | medicine.medical_specialty, Thrombotic microangiopathy, Kidney, Gastroenterology, Medical and Health Sciences, Tacrolimus, Article, Internal medicine, medicine, Coagulopathy, Humans, Transplantation, Homologous, Kidney transplantation, Transplantation, medicine.diagnostic_test, Platelet Count, SARS-CoV-2, Thrombotic Microangiopathies, business.industry, Acute kidney injury, COVID-19, Microangiopathic hemolytic anemia, Middle Aged, medicine.disease, Kidney Transplantation, Pancreatitis, Creatinine, Kidney Failure, Chronic, Acute pancreatitis, Female, Surgery, Renal biopsy, business |
| الوصف: | Coronavirus disease 2019 (COVID-19) is associated with high morbidity and mortality worldwide in both the general population and kidney transplant recipients. Acute kidney injury is a known complication of COVID-19 and appears to most commonly manifest as acute tubular injury on renal biopsy. Coagulopathy associated with COVID-19 is a known but poorly understood complication that has been reported to cause thrombotic microangiopathy on rare occasions in native kidneys of patients with COVID-19. Here, we report the first case of biopsy-proven thrombotic microangiopathy in a kidney transplant recipient with COVID-19 who developed acute pancreatitis and clinical features of microangiopathic hemolytic anemia. The patient recovered with supportive care alone. Highlights • Kidney transplant recipients with coronavirus disease 2019 (COVID-19) demonstrate higher mortality rates compared to the general population and frequent allograft dysfunction. • COVID-19 can cause a wide spectrum of extrapulmonary involvement, including coagulopathy, gastrointestinal symptoms, and acute kidney injury. • When diagnosing and treating kidney transplant recipients with acute allograft dysfunction in the setting of COVID-19, thrombotic microangiopathy should be considered. |
| وصف الملف: | application/pdf |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5c389f1538d88a4976675e897d625f7 https://escholarship.org/uc/item/9j58n3pn |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....f5c389f1538d88a4976675e897d625f7 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |