Hashimoto Thyroiditis: Part 2, Sonographic Analysis of Benign and Malignant Nodules in Patients With Diffuse Hashimoto Thyroiditis
| العنوان: | Hashimoto Thyroiditis: Part 2, Sonographic Analysis of Benign and Malignant Nodules in Patients With Diffuse Hashimoto Thyroiditis |
|---|---|
| المؤلفون: | Margaret M. Szabunio, Susan J. Mandel, William D. Middleton, Charles F. Hildebolt, Sharlene A. Teefey, John J. Cronan, Carl C. Reading, Terry S. Desser, Jill E. Langer, Lauren Anderson |
| المصدر: | American Journal of Roentgenology. 195:216-222 |
| بيانات النشر: | American Roentgen Ray Society, 2010. |
| سنة النشر: | 2010 |
| مصطلحات موضوعية: | Adult, Male, Thyroid nodules, endocrine system, Pathology, medicine.medical_specialty, endocrine system diseases, Adenoma, Biopsy, Fine-Needle, Hashimoto Disease, Diagnosis, Differential, Biopsy, medicine, Humans, Radiology, Nuclear Medicine and imaging, Thyroid Neoplasms, Thyroid Nodule, Thyroid cancer, Aged, Aged, 80 and over, medicine.diagnostic_test, business.industry, Thyroid, Cancer, Ultrasonography, Doppler, General Medicine, Middle Aged, Hyperplasia, medicine.disease, Lymphoma, medicine.anatomical_structure, Female, business |
| الوصف: | The purpose of this article is to compare sonographic features of benign and malignant nodules in patients with diffuse Hashimoto thyroiditis.As part of an ongoing multiinstitutional study, patients who underwent ultrasound and fine-needle aspiration of one or more thyroid nodules were analyzed for a variety of predetermined sonographic features. Patients with a sonographic appearance consistent with diffuse Hashimoto thyroiditis and with coexisting nodules that could be confirmed to be benign or malignant by fine-needle aspiration or surgical pathologic analysis were included in the study.Among nodules within diffuse Hashimoto thyroiditis, 84% (69/82) were benign (35 nodular Hashimoto thyroiditis, 32 nodular hyperplasia, and two follicular adenoma), and 16% (13/82) were malignant (12 papillary carcinoma and one lymphoma). Malignant nodules were more likely to be solid and hypoechoic (62% vs 19%). All types of calcifications were more prevalent among malignant nodules, including microcalcifications (39% vs 0%), nonspecific tiny bright reflectors (39% vs 6%), macrocalcifications (15% vs 3%), and eggshell (15% vs 2%). Benign nodules were more likely to be hyperechoic (46% vs 9%), to have a halo (39% vs 15%), and to lack calcifications (88% vs 23%). Benign nodules more often had ill-defined margins (36% vs 8%).Sonographic features of benign and malignant nodules within diffuse Hashimoto thyroiditis are generally similar to the features typical of benign and malignant nodules in the general population. If calcifications of any type are added to the list of malignant sonographic features, the decision to biopsy a nodule in patients with diffuse Hashimoto thyroiditis can be based on recommendations that have been published previously. |
| تدمد: | 1546-3141 0361-803X |
| DOI: | 10.2214/ajr.09.3680 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5bd208b82aff6021ef5020519b86a47 https://doi.org/10.2214/ajr.09.3680 |
| رقم الانضمام: | edsair.doi.dedup.....f5bd208b82aff6021ef5020519b86a47 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15463141 0361803X |
|---|---|
| DOI: | 10.2214/ajr.09.3680 |