Assessment of parametrial invasion of cervical carcinoma, the role of T2-weighted MRI and diffusion weighted imaging with or without fusion
| العنوان: | Assessment of parametrial invasion of cervical carcinoma, the role of T2-weighted MRI and diffusion weighted imaging with or without fusion |
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| المؤلفون: | Frans C. H. Bakers, T Van Gorp, J. E. Mongula, Brigitte F. M. Slangen, Roy F.P.M. Kruitwagen, Casper Mihl |
| المساهمون: | Promovendi ODB, MUMC+: MA Arts Assistenten Obstetrie Gynaecologie (9), RS: GROW - R2 - Basic and Translational Cancer Biology, MUMC+: DA BV Medisch Specialisten Radiologie (9), Beeldvorming, Obstetrie & Gynaecologie, MUMC+: MA Obstetrie Gynaecologie (3), MUMC+: MA Niet Med Staf Onderz Beh Obstetrie Gyn (9), MUMC+: MA Toegelatenen Obstetrie Gynaecologie (9), MUMC+: MA Medische Staf Obstetrie Gynaecologie (9) |
| المصدر: | Clinical Radiology, 74(10), 790-796. Elsevier Saunders |
| بيانات النشر: | Elsevier Saunders, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Adult, medicine.medical_specialty, Uterine Cervical Neoplasms, Hysterectomy, Preoperative care, RADICAL SURGERY, THERAPY, 030218 nuclear medicine & medical imaging, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Predictive Value of Tests, Preoperative Care, medicine, Humans, Neoplasm Invasiveness, Radiology, Nuclear Medicine and imaging, Radical surgery, Aged, Aged, 80 and over, Cervical cancer, Receiver operating characteristic, medicine.diagnostic_test, IMPROVING TUMOR-DETECTION, Parametrial, business.industry, Magnetic resonance imaging, General Medicine, Middle Aged, IB1, medicine.disease, Magnetic Resonance Imaging, CANCER, Diffusion Magnetic Resonance Imaging, 030220 oncology & carcinogenesis, Predictive value of tests, Female, Radiology, Peritoneum, business, Diffusion MRI |
| الوصف: | AIM: To evaluate the diagnostic performance of diffusion-weighted imaging (DWI), with and without fusion images, in addition to regular T2-weighted (T2W) sequences for assessment of parametrial invasion.MATERIALS AND METHODS: This prospective cohort included cervical cancer patients who underwent preoperative magnetic resonance imaging (MRI) with T2W and axial DWI sequences prior to radical hysterectomy. Retrospectively, two radiologists independently and blindly scored the likelihood of parametrial invasion by means of a six-point confidence scale. Parametrial invasion was determined by surgical-pathological results. Performance indices for diagnostic tests and area under the receiver operating characteristic curve (AUC) analyses were performed. P-Values ofRESULTS: Of 65 included patients, parametrial invasion was found in eight patients. A statistically significant increase in diagnostic performance for the assessment of parametrial invasion was found when T2W MRI was fused with DWI (fusion T2W/DWI), especially decreasing false-positive findings: the positive predictive value of parametrial invasion using T2W MRI versus fusion T2W MRI/DWI increased from 29% to 50% for observer 1 and from 23% to 50% for observer 2 (AUC=0.80-0.67 versus 0.94-0.94).CONCLUSIONS: Fusion T2W MRI/DWI shows a significant increase in diagnostic performance for the assessment of parametrial invasion in early-stage cervical carcinoma. (C) 2019 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1365-229X 0009-9260 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f414e036951ac1bf7d22c66a44630238 https://cris.maastrichtuniversity.nl/en/publications/579581f6-a441-4314-aeb4-0022eea3ed92 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....f414e036951ac1bf7d22c66a44630238 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1365229X 00099260 |
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