PURPOSE: To evaluate agreement in keratometry readings and anterior and posterior elevation map measurements among the Galilei V4.01 (Ziemer), Orbscan IIz (Bausch & Lomb), and Corneal Map topographer (Costruzione Strumenti Oftalmici) systems. METHODS: This prospective comparative study comprised 184 eyes of 92 consecutive refractive surgery candidates who were simultaneously examined with the Galilei (dual Scheimpflug), Orbscan II (scanning-slit), and Corneal Map topographer (Placido disk–based) systems. Keratometry readings and anterior and posterior elevation map measurements were compared using analysis of variance and paired t test, respectively. RESULTS: Mean keratometry reading was 44.30±1.49 diopters (D), 44.11±1.47 D, and 44.60±1.56 D with the Galilei, Orbscan, and Corneal Map topographer, respectively. Despite a significant difference in mean keratometry ( P CONCLUSIONS: Despite significant differences in mean keratometry readings and anterior and posterior elevation measurements among the three systems, the keratometry readings can be used interchangeably, as this difference is not clinically significant.