Quantitative and regiocontrolled cross-photocycloaddition of the anticancer drug 5-fluorouracil achieved in a cocrystal

التفاصيل البيبلوغرافية
العنوان: Quantitative and regiocontrolled cross-photocycloaddition of the anticancer drug 5-fluorouracil achieved in a cocrystal
المؤلفون: Shawna J. Dudovitz, Roxanne L. Dudovitz, Andrew J. E. Duncan, S. V. Santhana Mariappan, Jelena Stojaković, Leonard R. MacGillivray
المصدر: Chemical Communications. 52:13109-13111
بيانات النشر: Royal Society of Chemistry (RSC), 2016.
سنة النشر: 2016
مصطلحات موضوعية: Models, Molecular, Ethylene, Molecular Conformation, Solid-state, Antineoplastic Agents, 010402 general chemistry, 01 natural sciences, Cocrystal, Catalysis, chemistry.chemical_compound, Materials Chemistry, medicine, Organic chemistry, Cycloaddition Reaction, 010405 organic chemistry, Metals and Alloys, Stereoisomerism, General Chemistry, Photochemical Processes, Anticancer drug, 0104 chemical sciences, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, chemistry, Fluorouracil, Yield (chemistry), Ceramics and Composites, Crystallization, medicine.drug
الوصف: We describe a [2+2] cross-photocycloaddition of the anticancer drug 5-fluorouracil in the solid state that proceeds regioselectively and in quantitative yield. The photocycloaddition occurs in a cocrystal with trans-2,2'-bis(pyridyl)ethylene.
تدمد: 1364-548X
1359-7345
DOI: 10.1039/c6cc06570h
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef9fd14812bd8460b6ebdf0148737913
https://doi.org/10.1039/c6cc06570h
رقم الانضمام: edsair.doi.dedup.....ef9fd14812bd8460b6ebdf0148737913
قاعدة البيانات: OpenAIRE
الوصف
تدمد:1364548X
13597345
DOI:10.1039/c6cc06570h