Association of Ultrapure Citicoline, Homotaurine and Vitamin E in the Management of Normotensive Glaucoma: A Case Report
| العنوان: | Association of Ultrapure Citicoline, Homotaurine and Vitamin E in the Management of Normotensive Glaucoma: A Case Report |
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| المؤلفون: | Verdina, T., Passarelli, N., Carlini, A., Chemello, F., Mastropasqua, R., Cavallini, G. M. |
| المصدر: | Case Reports in Ophthalmology, Vol 11, Iss 2, Pp 222-228 (2020) Case Reports in Ophthalmology |
| بيانات النشر: | Karger Publishers, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | visual field, Intraocular pressure, medicine.medical_specialty, genetic structures, medicine.medical_treatment, Citicoline, Homotaurine, Neuroprotection, Normotensive glaucoma, Visual field, Brinzolamide, Glaucoma, Case Report, 01 natural sciences, normotensive glaucoma, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, lcsh:Ophthalmology, Ophthalmology, Normal tension glaucoma, medicine, 0101 mathematics, homotaurine, Glaucoma medication, business.industry, Brimonidine, 010102 general mathematics, medicine.disease, citicoline, eye diseases, chemistry, lcsh:RE1-994, 030221 ophthalmology & optometry, neuroprotection, sense organs, business, medicine.drug |
| الوصف: | Normal tension glaucoma (NTG) remains a therapeutic challenge for the ophthalmologist since there are no effective therapies as the main therapeutic target, i.e., the intraocular pressure (IOP) increase, is missed. We report on the effectiveness of two neuroprotective molecules (ultrapure citicoline plus homotaurine), in combination with a topical hypotensive approach, in the management of NTG in a long-term follow-up (30 months). A 38-year-old Caucasian woman with no significant medical history and a diagnosis of NTG, after an extensive 30-month treatment with oral dietary supplement containing ultrapure citicoline 500 mg, homotaurine 50 mg and vitamin E once per day and topical glaucoma medication (brimonidine + brinzolamide drops twice per day), presented a significantly improved automated 24-2 visual field with a controlled tonometric measurement associated with a stabilization of retinal fiber layer and ganglion cells at OCT examination with patient satisfaction. This finding suggests that ultrapure citicoline together with homotaurine and vitamin E, through a synergistic neuroprotective effect, could be a promising approach in the management of NTG. |
| اللغة: | English |
| تدمد: | 1663-2699 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ede655f7ee23120031f9e00e6b0443c0 https://www.karger.com/Article/FullText/507881 |
| Rights: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....ede655f7ee23120031f9e00e6b0443c0 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16632699 |
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