A Comparative Study of Perfusion Measurement in Brain Tumours at 3 Tesla MR: Arterial Spin Labeling versus Dynamic Susceptibility Contrast-Enhanced MRI
العنوان: | A Comparative Study of Perfusion Measurement in Brain Tumours at 3 Tesla MR: Arterial Spin Labeling versus Dynamic Susceptibility Contrast-Enhanced MRI |
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المؤلفون: | Alexis Bruniau, Guillaume Saliou, M. Perrin, G. De Marco, Souraya Stoquart-ElSankari, P. Monet, Jean-Noël Vallée, Pierre Lehmann |
المساهمون: | Service de radiologie, CHU Amiens-Picardie, Centre de Recherche sur le Sport et le Mouvement (CeRSM), Université Paris Nanterre (UPN) |
المصدر: | European Neurology European Neurology, Karger, 2010, 64 (1), pp.21-26. ⟨10.1159/000311520⟩ European Neurology, 2010, 64 (1), pp.21-26. ⟨10.1159/000311520⟩ |
بيانات النشر: | S. Karger AG, 2010. |
سنة النشر: | 2010 |
مصطلحات موضوعية: | Adult, Male, Arterial spin labeling, [SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging, Contrast Media, 030218 nuclear medicine & medical imaging, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Image Processing, Computer-Assisted, Cerebral neoplasm, [SDV.MHEP.PHY]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO], otorhinolaryngologic diseases, Humans, 3T MR, Medicine, Correlation test, Aged, Retrospective Studies, Aged, 80 and over, Brain Neoplasms, business.industry, Dynamic Susceptibility Contrast-Enhanced MRI, [SPI.MECA.BIOM]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Biomechanics [physics.med-ph], Arteries, Middle Aged, Cerebral blood flow, Magnetic Resonance Imaging, Perfusion, Contrast medium, Neurology, Cerebrovascular Circulation, Female, Spin Labels, Neurology (clinical), Nuclear medicine, business, 030217 neurology & neurosurgery, Dynamic susceptibility |
الوصف: | Purpose: To prove the feasibility of arterial spin labeling (ASL) to explore brain tumors by comparing dynamic susceptibility contrast-enhanced MRI to ASL at 3T MR. Materials and Methods: Twenty-seven patients were included presenting 9 gliomas, 10 metastases and 8 meningiomas. All were explored by a pseudo-continuous ASL and dynamic susceptibility contrast-enhanced T2* perfusion sequence. Two neuroradiologists analyzed the cerebral blood flow (CBF) maps to assess feasibility, examination quality and quantitative comparison. The Spearman nonparametric correlation test and the Bland-Altman graphic test were used to analyze our quantitative results. Results: 92% of ASL CBF maps were informative. ASL detected all lesions as well as dynamic susceptibility contrast-enhanced MRI. Both sequences provide relative quantitative CBF values closely correlated. Conclusion: On a 3T MR unit, ASL is a good alternative to dynamic susceptibility contrast-enhanced MRI when contrast medium is contraindicated or intravenous injection is not possible. Its results on relative CBF parameters are similar to contrast-injected perfusion. |
تدمد: | 1421-9913 0014-3022 |
DOI: | 10.1159/000311520 |
DOI: | 10.1159/000311520⟩ |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb0939e74a18eaaf33c154d473e48061 https://doi.org/10.1159/000311520 |
Rights: | OPEN |
رقم الانضمام: | edsair.doi.dedup.....eb0939e74a18eaaf33c154d473e48061 |
قاعدة البيانات: | OpenAIRE |
تدمد: | 14219913 00143022 |
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DOI: | 10.1159/000311520 |